Cat: PAX2000-12720

Recombinant Human ZMYM3 Protein,GST

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Analytical Data

  • Gene name

    ZMYM3

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    DXS6673E; KIAA0385; MYM; XFIM; ZFP261; Zinc finger MYM type 3; Zinc finger MYM type Protein 3; Zinc finger MYM-type Protein 3; Zinc finger Protein 261; ZMYM 3; Zmym3; ZMYM3_HUMAN; ZNF 261; ZNF198L2; ZNF261

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q14202

  • Expression Region

    1-495 aa

  • AA Sequence

    MDPSDFPSPFDPLTLPEKPLAGDLPVDMEFGEDLLESQTAPTRGWAPPGPSPSSGALDLLDTPAGLEKDPGVLDGATELLGLGGLLYKAPSPPEVDHGPEGTLAWDAGDQTLEPGPGGQTPEVVPPDPGAGANSCSPEGLLEPLAPDSPITLQSPHIEEEETTSIATARRGSPGQEEELPQGQPQSPNAPPSPSVGETLGDGINSSQTKPGGSSPPAHPSLPGDGLTAKASEKPPERKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMSLRSSVSQRAGRSAVGTKMTCAHCRTPLQKGQTAYQRKGLPQLFCSSSCLTTFSKKPSGKKTCTFCKKEIWNTKDSVVAQTGSGGSFHEFCTSVCLSLYEAQQQRPIPQSGDPADATRCSICQKTGEVLHEVSNGSVVHRLCSDSCFSKFRANKGLKTNCCDQCGAYIYTKTGSPGPELLFHEGQQKRFCNTTCLGAYKKVGPRE

  • Molecular Weight

    78.9 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

ZMYM3 (Zinc Finger MYM-Type 3) is a member of the MYM-type zinc finger protein family, which is implicated in various biological processes including transcriptional regulation and chromatin remodeling. Research into ZMYM3 has gained significance due to its potential role in cancer biology and developmental disorders. Mutations and altered expression levels of ZMYM3 have been associated with several malignancies, suggesting its involvement in tumorigenesis. Additionally, studies have revealed that ZMYM3 interacts with key proteins involved in cell cycle regulation and apoptotic pathways, indicating its functional relevance in cellular homeostasis. Furthermore, as a transcriptional co-regulator, ZMYM3 may influence gene expression related to cellular growth and differentiation. Understanding the structure-function relationships of ZMYM3 through recombinant protein studies could provide insights into its biological roles and aid in the identification of therapeutic targets for cancer treatment and other diseases linked to its dysregulation. Overall, the investigation of ZMYM3 and its recombinantly expressed proteins is crucial for elucidating its mechanisms in health and disease and may pave the way for novel strategies in disease management.

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