Analytical Data
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基因名
ZHX3
- Application
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别名
KIAA0395; TIX1; Triple homeobox 1; Triple homeobox Protein 1; ZHX 3; Zhx3; ZHX3_HUMAN; Zinc finger and homeodomain Protein 3; Zinc fingers and homeoboxes Protein 3
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H4I2
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表达区间
1-969 aa
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氨基酸序列
MASKRKSTTPCMIPVKTVVLQDASMEAQPAETLPEGPQQDLPPEASAASSEAAQNPSSTDGSTLANGHRSTLDGYLYSCKYCDFRSHDMTQFVGHMNSEHTDFNKDPTFVCSGCSFLAKTPEGLSLHNATCHSGEASFVWNVAKPDNHVVVEQSIPESTSTPDLAGEPSAEGADGQAEIIITKTPIMKIMKGKAEAKKIHTLKENVPSQPVGEALPKLSTGEMEVREGDHSFINGAVPVSQASASSAKNPHAANGPLIGTVPVLPAGIAQFLSLQQQPPVHAQHHVHQPLPTAKALPKVMIPLSSIPTYNAAMDSNSFLKNSFHKFPYPTKAELCYLTVVTKYPEEQLKIWFTAQRLKQGISWSPEEIEDARKKMFNTVIQSVPQPTITVLNTPLVASAGNVQHLIQAALPGHVVGQPEGTGGGLLVTQPLMANGLQATSSPLPLTVTSVPKQPGVAPINTVCSNTTSAVKVVNAAQSLLTACPSITSQAFLDASIYKNKKSHEQLSALKGSFCRNQFPGQSEVEHLTKVTGLSTREVRKWFSDRRYHCRNLKGSRAMIPGDHSSIIIDSVPEVSFSPSSKVPEVTCIPTTATLATHPSAKRQSWHQTPDFTPTKYKERAPEQLRALESSFAQNPLPLDEEMDRLRSETKMTRREIDSWFSERRKKVNAEETKKAEENASQEEEEAAEDEGGEEDLASELRVSGENGSLEMPSSHILAERKVSPIKINLKNLRVTEANGRNEIPGLGACDPEDDESNKLAEQLPGKVSCKKTAQQRHLLRQLFVQTQWPSNQDYDSIMAQTGLPRPEVVRWFGDSRYALKNGQLKWYEDYKRGNFPPGLLVIAPGNRELLQDYYMTHKMLYEEDLQNLCDKTQMSSQQKQTEFDLINVKDWPVWETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG
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分子量
132.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZHX3 (Zinc Finger Homeobox 3) is a member of the ZHX family of transcription factors, which are characterized by their zinc finger DNA-binding domains and homeobox motifs. Research into ZHX3 has gained attention due to its critical role in various biological processes, including cell differentiation, organ development, and metabolic regulation. Notably, ZHX3 has been implicated in the pathogenesis of several diseases, such as obesity, diabetes, and certain types of cancer, highlighting its potential as a therapeutic target. Studies have shown that ZHX3 acts as a transcriptional repressor, regulating the expression of genes involved in insulin signaling and lipid metabolism. This function positions ZHX3 as a key factor in maintaining metabolic homeostasis. Furthermore, the understanding of ZHX3’s regulatory mechanisms could provide insights into how disruptions in its activity are linked to metabolic disorders. Given its multifaceted role in health and disease, the recombinant expression and functional characterization of ZHX3 protein has become a focal point in molecular biology and biomedicine. By producing ZHX3 in a recombinant system, researchers can investigate its structure-function relationships, explore its interactions with other proteins, and assess its effects on gene expression in cellular models. This line of research not only sheds light on the biological significance of ZHX3 but also opens avenues for potential interventions in diseases connected to its dysregulation. Thus, the study of recombinant ZHX3 protein is critical for advancing our understanding of its role in physiology and pathology.
