Analytical Data
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基因名
TIGD4
- Application
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别名
TIGD4; Tigger transposable element-derived Protein 4
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8IY51
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表达区间
1-512 aa
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氨基酸序列
MAEASVDAST LPVTVKKKKS LSIEEKIDII NAVESGKKKA EIAAEYGIKK NSLSSIMKNK DKVLEAFESL RFDPKRKRLR TAFYTDLEEA LMRWYRIAQC LNVPVNGPML RLKANDFAQK LGHNDFKCSN GWLDRFKSRY GLVFRAQPVE ATGVPVDPST VWYQNVLPYY LNDYHPKNVF NIKETGLLYR MLPTNTFAFK GETCSVGKLC KDRITLVVGT NMDGSEKLPL LVIGKKRTPH CFKGLKSLPV CYEANRMAWM TSDVFEQWMR KLDEEFQAQQ RRVVIFVESF PAHPEVKNLK SIELAFFPSC LSSKCIAMKQ GVIKSLKIKY RHCLIKKFLS SVEGSKEFTF SLLDAVDTLH LCWRAVTPET IVKSYEEAGF KSQKGESDIT NAEKDTGLDL VADALGAGVE FPEGLSIEEY AALDDDLETC EAAPNGDSIC TKESKSDETG FYTSDEEDDD GSPGTELPLP SKSEAITALD TLKKFLRSQD MNDGLQNSLA DLENFINSLS PK
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分子量
57.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TIGD4, or T-cell immunoglobulin and mucin-domain containing protein 4, is a member of the immunoglobulin superfamily and has garnered significant interest in immunological research due to its role in modulating immune responses. Originally identified as a cell surface protein expressed on T cells, TIGD4 participates in various cellular processes, including T-cell activation, proliferation, and differentiation. Its expression is not limited to T cells; it has also been implicated in other immune cell types, suggesting a broader role in the immune system. Recent studies indicate that TIGD4 may interact with specific ligands and participate in signaling pathways that influence the immune response to pathogens and tumors. Furthermore, its potential association with autoimmune diseases and cancers has prompted researchers to explore the therapeutic applications of TIGD4-targeting strategies. The recombinant expression of TIGD4 protein provides a valuable tool for studying its structure-function relationships, interactions with other proteins, and its role in immune modulation. By producing and characterizing TIGD4 recombinant protein, researchers aim to elucidate its biological functions and its implications in disease mechanisms, paving the way for novel immunotherapeutic approaches. Understanding TIGD4's precise role in the immune system may lead to innovative strategies for enhancing immune response during infections or suppressing it in the context of autoimmune diseases.
