Analytical Data
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Gene name
TIGD4
- Application
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Alternative Names
TIGD4; Tigger transposable element-derived Protein 4
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8IY51
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Expression Region
1-512 aa
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AA Sequence
MAEASVDAST LPVTVKKKKS LSIEEKIDII NAVESGKKKA EIAAEYGIKK NSLSSIMKNK DKVLEAFESL RFDPKRKRLR TAFYTDLEEA LMRWYRIAQC LNVPVNGPML RLKANDFAQK LGHNDFKCSN GWLDRFKSRY GLVFRAQPVE ATGVPVDPST VWYQNVLPYY LNDYHPKNVF NIKETGLLYR MLPTNTFAFK GETCSVGKLC KDRITLVVGT NMDGSEKLPL LVIGKKRTPH CFKGLKSLPV CYEANRMAWM TSDVFEQWMR KLDEEFQAQQ RRVVIFVESF PAHPEVKNLK SIELAFFPSC LSSKCIAMKQ GVIKSLKIKY RHCLIKKFLS SVEGSKEFTF SLLDAVDTLH LCWRAVTPET IVKSYEEAGF KSQKGESDIT NAEKDTGLDL VADALGAGVE FPEGLSIEEY AALDDDLETC EAAPNGDSIC TKESKSDETG FYTSDEEDDD GSPGTELPLP SKSEAITALD TLKKFLRSQD MNDGLQNSLA DLENFINSLS PK
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Molecular Weight
57.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TIGD4, or T-cell immunoglobulin and mucin-domain containing protein 4, is a member of the immunoglobulin superfamily and has garnered significant interest in immunological research due to its role in modulating immune responses. Originally identified as a cell surface protein expressed on T cells, TIGD4 participates in various cellular processes, including T-cell activation, proliferation, and differentiation. Its expression is not limited to T cells; it has also been implicated in other immune cell types, suggesting a broader role in the immune system. Recent studies indicate that TIGD4 may interact with specific ligands and participate in signaling pathways that influence the immune response to pathogens and tumors. Furthermore, its potential association with autoimmune diseases and cancers has prompted researchers to explore the therapeutic applications of TIGD4-targeting strategies. The recombinant expression of TIGD4 protein provides a valuable tool for studying its structure-function relationships, interactions with other proteins, and its role in immune modulation. By producing and characterizing TIGD4 recombinant protein, researchers aim to elucidate its biological functions and its implications in disease mechanisms, paving the way for novel immunotherapeutic approaches. Understanding TIGD4's precise role in the immune system may lead to innovative strategies for enhancing immune response during infections or suppressing it in the context of autoimmune diseases.
