Analytical Data
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基因名
ZFYVE19
- Application
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别名
Abscission/NoCut checkpoint regulator; ANCHR; MLL partner containing FYVE domain; MPFYVE; ZFY19_HUMAN; ZFYVE 19; Zfyve19; Zinc finger FYVE domain containing Protein 19; Zinc finger FYVE domain-containing Protein 19; Zinc finger FYVE type containing 19; Zinc finger; FYVE domain containing 19
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96K21
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表达区间
1-396 aa
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氨基酸序列
MESRCYGCAVKFTLFKKEYGCKNCGRAFCSGCLSFSAAVPRTGNTQQKVCKQCHEVLTRGSSANASKWSPPQNYKKRVAALEAKQKPSTSQSQGLTRQDQMIAERLARLRQENKPKLVPSQAEIEARLAALKDERQGSIPSTQEMEARLAALQGRVLPSQTPQPAHHTPDTRTQAQQTQDLLTQLAAEVAIDESWKGGGPAASLQNDLNQGGPGSTNSKRQANWSLEEEKSRLLAEAALELREENTRQERILALAKRLAMLRGQDPERVTLQDYRLPDSDDDEDEETAIQRVLQQLTEEAALDEASGFNIPAEQASRPWTQPRGAEPEAQDVDPRPEAEEEELPWCCICNEDATLRCAGCDGDLFCARCFREGHDAFELKEHQTSAYSPPRAGQEH
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分子量
69.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZFYVE19, a member of the zinc-finger and FYVE domain-containing proteins, has garnered attention in recent years due to its potential role in various cellular processes and disease mechanisms. Initially identified through genomic studies, ZFYVE19 is believed to be involved in cellular signaling pathways, membrane trafficking, and possibly in the regulation of autophagy. Research has indicated that alterations in ZFYVE19 expression may be linked to specific pathologies, including cancer and neurodegenerative disorders. Its unique structure, featuring both zinc-finger motifs and FYVE domains, suggests a multifunctional role that could be crucial for maintaining cellular homeostasis. The functional characterization of ZFYVE19 and the development of recombinant protein versions have become pivotal for elucidating its biological roles. Laboratory studies employing techniques such as protein expression, purification, and interaction assays are essential to understand the protein's mechanisms of action, its interactions with other cellular components, and the potential implications for therapeutic strategies. Overall, comprehensively studying ZFYVE19 and its recombinant forms offers valuable insights into its contribution to health and disease, making it a significant target for future research endeavors.
