Analytical Data
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Gene name
THAP5
- Application
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Alternative Names
THAP5; THAP domain-containing Protein 5
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q7Z6K1
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Expression Region
1-395 aa
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AA Sequence
MPRYCAAICC KNRRGRNNKD RKLSFYPFPL HDKERLEKWL KNMKRDSWVP SKYQFLCSDH FTPDSLDIRW GIRYLKQTAV PTIFSLPEDN QGKDPSKKKS QKKNLEDEKE VCPKAKSEES FVLNETKKNI VNTDVPHQHP ELLHSSSLVK PPAPKTGSIQ NNMLTLNLVK QHTGKPESTL ETSVNQDTGR GGFHTCFENL NSTTITLTTS NSESIHQSLE TQEVLEVTTS HLANPNFTSN SMEIKSAQEN PFLFSTINQT VEELNTNKES VIAIFVPAEN SKPSVNSFIS AQKETTEMED TDIEDSLYKD VDYGTEVLQI EHSYCRQDIN KEHLWQKVSK LHSKITLLEL KEQQTLGRLK SLEALIRQLK QENWLSEENV KIIENHFTTY EVTMI
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Molecular Weight
45.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
THAP5, a member of the THAP (THAP-type zinc finger) protein family, has garnered significant interest in molecular and cellular biology due to its crucial role in gene regulation and development. Initially identified as a transcription factor, THAP5 is implicated in various biological processes, including cell proliferation, differentiation, and apoptosis. Studies have suggested that THAP5 may interact with specific DNA sequences, influencing the expression of target genes involved in these processes. Its expression patterns are tightly regulated during embryogenesis and in differentiated tissues, indicating its potential significance in developmental biology. Additionally, emerging evidence suggests that dysregulation of THAP5 may contribute to various pathologies, including cancer and neurodegenerative diseases, highlighting its importance as a therapeutic target. To better understand THAP5's function at the molecular level, researchers have focused on producing recombinant THAP5 protein, which enables detailed studies of its DNA-binding capabilities, protein-protein interactions, and regulatory mechanisms. These investigations are crucial for elucidating the biological roles of THAP5 and its potential implications in health and disease.
