Analytical Data
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基因名
PTTG1IP
- Application
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别名
PTTG1IP；C21orf1；C21orf3；Pituitary tumor-transforming gene 1 Protein-interacting Protein
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P53801
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表达区间
1-180aa
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氨基酸序列
MAPGVARGPTPYWRLRLGGAALLLLLIPVAAAQEPPGAACSQNTNKTCEECLKNVSCLWCNTNKACLDYPVTSVLPPASLCKLSSARWGVCWVNFEALIITMSVVGGTLLLGIAICCCCCCRRKRSRKPDRSEEKAMREREERRIRQEERRAEMKTRHDEIRKKYGLFKEENPYARFENN
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分子量
20.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PTTG1IP (PTTG1-interacting protein) is a notable protein that plays a crucial role in cell cycle regulation and tumorigenesis. Initially identified as a binding partner of the pituitary tumor-transforming gene 1 (PTTG1), PTTG1IP has been implicated in various cellular processes, including cell proliferation, apoptosis, and chromosomal stability. Research has shown that alterations in the expression levels of PTTG1IP can influence cancer progression, particularly in tumors of the breast, thyroid, and other tissues. Given its potential as a biomarker for cancer diagnosis and prognosis, as well as a therapeutic target, the recombinant expression of PTTG1IP has become a focus of scientific inquiry. Understanding its structure and function through recombinant protein techniques can provide insight into its role in oncogenesis and pave the way for the development of novel cancer treatment strategies. Additionally, the study of PTTG1IP may reveal new pathways that are essential for maintaining cellular homeostasis and could identify critical interactions that could be targeted in various malignancies. Therefore, the investigation of PTTG1IP as a recombinant protein offers promising avenues for enhancing our understanding of tumor biology and improving clinical outcomes for cancer patients.
