Analytical Data
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Gene name
TFCP2
- Application
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Alternative Names
Alpha globin transcription factor CP2; Alpha-globin transcription factor CP2; CP2; Late SV40 factor; LBP 1C; LBP1C; LSF; LSF1D; SAA3 enhancer factor; SEF; TFCP2; TFCP2_HUMAN; TFCP2C; Transcription factor CP2; Transcription factor LSF
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q12800
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Expression Region
1-502 aa
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AA Sequence
MAWALKLPLA DEVIESGLVQ DFDASLSGIG QELGAGAYSM SDVLALPIFK QEESSLPPDN ENKILPFQYV LCAATSPAVK LHDETLTYLN QGQSYEIRML DNRKLGELPE INGKLVKSIF RVVFHDRRLQ YTEHQQLEGW RWNRPGDRIL DIDIPMSVGI IDPRANPTQL NTVEFLWDPA KRTSVFIQVH CISTEFTMRK HGGEKGVPFR VQIDTFKENE NGEYTEHLHS ASCQIKVFKP KGADRKQKTD REKMEKRTPH EKEKYQPSYE TTILTECSPW PEITYVNNSP SPGFNSSHSS FSLGEGNGSP NHQPEPPPPV TDNLLPTTTP QEAQQWLHRN RFSTFTRLFT NFSGADLLKL TRDDVIQICG PADGIRLFNA LKGRMVRPRL TIYVCQESLQ LREQQQQQQQ QQQKHEDGDS NGTFFVYHAI YLEELTAVEL TEKIAQLFSI SPCQISQIYK QGPTGIHVLI SDEMIQNFQE EACFILDTMK AETNDSYHII LK
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Molecular Weight
57.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TFCP2, or Transcription Factor CP2, is a crucial protein involved in the regulation of various biological processes, including cell proliferation, differentiation, and development. It plays a significant role in the transcriptional regulation of genes associated with early embryonic development and stem cell maintenance. The study of TFCP2 has garnered attention due to its implications in various diseases, including cancer, where aberrant expression or mutations in TFCP2 have been linked to tumor progression and poor prognosis. Moreover, TFCP2 is known to interact with numerous other proteins and transcriptional complexes, further highlighting its importance in gene regulation. The recombinant production of TFCP2 is essential for elucidating its functional mechanisms and understanding its role in cellular processes. Researchers utilize recombinant techniques to produce TFCP2 in sufficient quantities for biochemical and structural studies, which may lead to the identification of novel therapeutic targets. Increasing the understanding of TFCP2’s structure-function relationship through recombinant protein studies could pave the way for innovative approaches to manipulate its activity in various pathological contexts, making it a valuable subject of research in molecular biology and therapeutic development.
