Analytical Data
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基因名
EFR3A
- Application
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别名
EFR3A; KIAA0143Protein EFR3 homolog A; Protein EFR3-like
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q14156
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表达区间
1-785aa
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氨基酸序列
MEKLTFYAVSAPEKLDRIGSYLAERLSRDVVRHRSGYVLIAMEALDQLLMACHSQSIKPFVESFLHMVAKLLESGEPKLQVLGTNSFVKFANIEEDTPSYHRRYDFFVSRFSAMCHSCHSDPEIRTEIRIAGIRGIQGVVRKTVNDELRATIWEPQHMDKIVPSLLFNMQKIEEVDSRIGPPSSPSATDKEENPAVLAENCFRELLGRATFGNMNNAVRPVFAHLDHHKLWDPNEFAVHCFKIIMYSIQAQYSHHVIQEILGHLDARKKDAPRVRAGIIQVLLEAVAIAAKGSIGPTVLEVFNTLLKHLRLSVEFEANDLQGGSVGSVDLNTSSKDNDEKIVQNAIIQTIGFFGSNLPDYQRSEIMMFIMGKVPVFGTSTHTLDISQLGDLGTRRIQIMLLRSLLMVTSGYKAKTIVTALPGSFLDPLLSPSLMEDYELRQLVLEVMHNLMDRHDNRAKLRGIRIIPDVADLKIKREKICRQDTSFMKKNGQQLYRHIYLGCKEEDNVQKNYELLYTSLALITIELANEEVVIDLIRLAIALQDSAIINEDNLPMFHRCGIMALVAAYLNFVSQMIAVPAFCQHVSKVIEIRTMEAPYFLPEHIFRDKCMLPKSLEKHEKDLYFLTNKIAESLGGSGYSVERLSVPYVPQVTDEDRLSRRKSIVDTVSIQVDILSNNVPSDDVVSNTEEITFEALKKAIDTSGMEEQEKEKRRLVIEKFQKAPFEEIAAQCESKANLLHDRLAQILELTIRPPPSPSGTLTITSGHAQYQSVPVYEMKFPDLCVY
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分子量
115.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
EFR3A is a protein that plays a crucial role in cellular signaling and has been identified as a key component in the regulation of various physiological processes. It has garnered attention in recent studies due to its involvement in the regulation of receptors, particularly in the context of G-protein coupled receptors (GPCRs), which are pivotal in mediating numerous cellular responses to external stimuli. The interest in EFR3A has been further amplified by its potential implications in diseases such as cancer and neurological disorders, where altered signaling pathways often play a critical role. Research has shown that EFR3A may influence the localization and function of certain receptors, thereby modulating their activity and ultimately affecting cellular behavior. Additionally, understanding the functional dynamics of EFR3A could provide insights into the broader mechanisms of signal transduction and its disruption in pathological conditions. As the characterization of EFR3A continues, the development of recombinant EFR3A protein has become a focal point to facilitate in-depth studies regarding its structure-function relationship, interaction with other signaling molecules, and its potential as a therapeutic target. The ability to produce this protein in a controlled environment paves the way for various biochemical assays, structural biology studies, and drug discovery efforts aimed at leveraging the unique properties of EFR3A for therapeutic advantage. Overall, research on EFR3A and its recombinant form represents a promising frontier in the understanding of complex cellular signaling networks and their implications for human health.
