Analytical Data
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基因名
ZCCHC6
- Application
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别名
TUT7; HS2; KIAA1711; ZCCHC6; Terminal uridylyltransferase 7; TUTase 7; EC 2.7.7.52; Zinc finger CCHC domain-containing Protein 6
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q5VYS8
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表达区间
1-412 aa
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氨基酸序列
MGDTAKPYFVKRTKDRGTMDDDDFRRGHPQQDYLIIDDHAKGHGSKMEKGLQKKKITPGNYGNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGPRIPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRSRPRKPRKTRNEENEQDGDLEGPVIDESVLSTKELLGLQQAEERLKRDCIDRLKRRPRNYPTAKYTCRLCDVLIESIAFAHKHIKEKRHKKNIKEKQEEELLTTLPPPTPSQINAVGIAIDKVVQEFGLHNENLEQRLEIKRIMENVFQHKLPDCSLRLYGSSCSRLGFKNSDVNIDIQFPAIMSQPDVLLLVQECLKNSDSFIDVDADFHARVPVVVCREKQRSHFFKLFIY
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分子量
74.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZCCHC6, a member of the zinc finger CCCH-type containing protein family, has garnered significant attention in recent years due to its potential roles in various biological processes, particularly in RNA metabolism and cellular stress responses. Research indicates that ZCCHC6 may influence mRNA stability and translation by interacting with specific RNA molecules, thereby impacting gene expression regulation. Additionally, studies have suggested that ZCCHC6 could be involved in the modulation of immune responses and in the regulation of cell proliferation, hinting at its relevance in cancer biology. Given the increasing prevalence of diseases linked to dysregulated gene expression, understanding the functional mechanisms of ZCCHC6 offers valuable insights into potential therapeutic targets. Furthermore, the protein's structural features, including the presence of multiple zinc finger motifs, suggest a sophisticated mechanism of action that warrants detailed investigation. As recombinant protein studies expand, efforts to elucidate the biochemical properties and interaction networks of ZCCHC6 will enhance our comprehension of its roles in health and disease, paving the way for future research avenues aimed at exploring its relevance in therapeutic strategies.
