Analytical Data
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Gene name
ZC3H15
- Application
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Alternative Names
ZC3H15; DFRP1; LEREPO4; HSPC303; HT010; MSTP012; PP730; Zinc finger CCCH domain-containing Protein 15; DRG family-regulatory Protein 1; Likely ortholog of mouse immediate early response erythropoietin 4
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8WU90
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Expression Region
1-426 aa
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AA Sequence
MPPKKQAQAGGSKKAEQKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQSEAEKKLKKDDKKKELQELNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLTLERKCEKRSVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVCKHFLEAIENNKYGWFWVCPGGGDICMYRHALPPGFVLKKDKKKEEKEDEISLEDLIERERSALGPNVTKITLESFLAWKKRKRQEKIDKLEQDMERRKADFKAGKALVISGREVFEFRPELVNDDDEEADDTRYTQGTGGDEVDDSVSVNDIDLSLYIPRDVDETGITVASLERFSTYTSDKDENKLSEASGGRAENGERSDLEEDNEREGTENGAIDAVPVDENLFTGEDLDELEEELNTLDLEE
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Molecular Weight
75 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZC3H15 is a zinc finger protein belonging to the ZC3H family, which plays a significant role in various cellular processes, including gene expression regulation, cell differentiation, and immune responses. This protein has gained attention in recent years due to its potential implications in pathophysiological conditions, particularly its association with various cancers and autoimmune diseases. Research shows that ZC3H15 can regulate mRNA stability and influence the splicing of pre-mRNA, highlighting its involvement in post-transcriptional regulation. Additionally, studies suggest that alterations in ZC3H15 expression levels may correlate with disease progression and severity, making it a candidate for further investigation as a biomarker or therapeutic target. As a recombinant protein, ZC3H15 is being explored for its biochemical properties and functional roles in cellular signaling pathways, which could provide insights into its mechanism of action. Overall, understanding the structure and function of ZC3H15 not only enhances our knowledge of its biological roles but also paves the way for developing novel strategies in disease treatment and management.
