Analytical Data
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基因名
GRM1
- Application
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别名
GRM1;GPRC1A;MGLUR1;Metabotropic glutamate receptor 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q13255
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表达区间
387-486aa
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氨基酸序列
NPNFKRICTGNESLEENYVQDSKMGFVINAIYAMAHGLQNMHHALCPGHVGLCDAMKPIDGSKLLDFLIKSSFIGVSGEEVWFDEKGDAPGRYDIMNLQY
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分子量
37 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GRM1, or glutamate receptor metabotropic 1, is a member of the metabotropic glutamate receptor family and plays a crucial role in neurotransmission and synaptic plasticity in the central nervous system. Aberrant GRM1 signaling has been implicated in various neurological disorders, including epilepsy, schizophrenia, and certain forms of cancer. The study of GRM1 recombinant proteins is significant for several reasons. Firstly, understanding the structure and function of GRM1 can provide insights into its role in neuronal signaling pathways and its contribution to neurophysiological processes. Additionally, the design and characterization of GRM1 recombinant proteins facilitate the development of targeted therapeutics that may modulate its activity in pathological conditions. By utilizing techniques such as protein expression in heterologous systems and functional assays, researchers aim to elucidate the pharmacological properties and interaction mechanisms of GRM1 with other cellular components. This information is essential for identifying potential drug candidates and understanding their therapeutic implications. Overall, the ongoing research on GRM1 recombinant proteins not only enhances our knowledge of glutamatergic signaling but also holds promise for developing innovative treatments for neuropsychiatric and neurodegenerative diseases.












