Analytical Data
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Gene name
ZBTB7B
- Application
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Alternative Names
Zinc finger Protein 857B; Zinc finger Protein Th POK; Zinc finger Protein Th-POK; Zinc finger Protein ThPOK; ZNF857B
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O15156
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Expression Region
1-539 aa
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AA Sequence
MGSPEDDLIGIPFPDHSSELLSCLNEQRQLGHLCDLTIRTQGLEYRTHRAVLAACSHYFKKLFTEGGGGAVMGAGGSGTATGGAGAGVCELDFVGPEALGALLEFAYTATLTTSSANMPAVLQAARLLEIPCVIAACMEILQGSGLEAPSPDEDDCERARQYLEAFATATASGVPNGEDSPPQVPLPPPPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEVPTVPAHPLTYEEEEVAGRVGSSGGSGPGDSYSPPTGTASPPEGPQSYEPYEGEEEEEELVYPPAYGLAQGGGPPLSPEELGSDEDAIDPDLMAYLSSLHQDNLAPGLDSQDKLVRKRRSQMPQECPVCHKIIHGAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCPHCPARFLHSYDLKNHMHLHTGDRPYECHLCHKAFAKEDHLQRHLKGQNCLEVRTRRRRKDDAPPHYPPPSTAAASPAGLDLSNGHLDTFRLSLARFWEQSAPTGPPVSTPGPPDDDEEEGAPTTPQAEGAMESS
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Molecular Weight
84.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZBTB7B, also known as ZBTB7A orOUF, is a member of the zinc finger and BTB/POZ domain-containing protein family, which plays crucial roles in gene regulation, cell differentiation, and immune responses. Research into ZBTB7B has gained momentum due to its involvement in various biological processes, including the modulation of oncogenic pathways and its association with specific cancers, particularly in hematological malignancies. The protein functions as a transcriptional repressor and has been implicated in the regulation of immune system development and function, particularly in T-cell differentiation. Given its central role in both normal physiological processes and pathological conditions, recombinant ZBTB7B protein has become a subject of significant interest for researchers investigating its structural and functional properties. Studying the recombinant form of ZBTB7B enables the exploration of its interactions with other proteins and DNA, thus providing insights into its regulatory mechanisms. Moreover, understanding how ZBTB7B operates in different cell types could unveil its therapeutic potential as a target for treating diseases linked to its dysregulation. Overall, the research on ZBTB7B recombinant protein not only enhances our knowledge of transcriptional regulation but also paves the way for novel approaches in cancer therapy and immunomodulation.
