Analytical Data
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Gene name
TBL1X
- Application
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Alternative Names
EBI; F box like/WD repeat protein TBL1X; F-box-like/WD repeat-containing protein TBL1X; SMAP 55; SMAP55; TBL 1; TBL 1X; TBL1; TBL1X; TBL1X_HUMAN; Transducin (beta) like 1; Transducin (beta) like 1 X linked; Transducin (beta) like 1X linked; Transducin beta like 1 X linked; Transducin beta like 1X; Transducin beta like 1X protein; Transducin beta like protein 1. X linked; Transducin beta-like protein 1X; Transducin-beta-like protein 1; X-linked
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O60907
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Expression Region
1-577 aa
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AA Sequence
MTELAGASSS CCHRPAGRGA MQSVLHHFQR LRGREGGSHF INTSSPRGEA KMSITSDEVN FLVYRYLQES GFSHSAFTFG IESHISQSNI NGTLVPPAAL ISILQKGLQY VEAEISINED GTVFDGRPIE SLSLIDAVMP DVVQTRQQAF REKLAQQQAS AAAAAAAATA AATAATTTSA GVSHQNPSKN REATVNGEEN RAHSVNNHAK PMEIDGEVEI PSSKATVLRG HESEVFICAW NPVSDLLASG SGDSTARIWN LNENSNGGST QLVLRHCIRE GGHDVPSNKD VTSLDWNTNG TLLATGSYDG FARIWTEDGN LASTLGQHKG PIFALKWNRK GNYILSAGVD KTTIIWDAHT GEAKQQFPFH SAPALDVDWQ NNTTFASCST DMCIHVCRLG CDRPVKTFQG HTNEVNAIKW DPSGMLLASC SDDMTLKIWS MKQEVCIHDL QAHNKEIYTI KWSPTGPATS NPNSNIMLAS ASFDSTVRLW DIERGVCTHT LTKHQEPVYS VAFSPDGKYL ASGSFDKCVH IWNTQSGNLV HSYRGTGGIF EVCWNARGDK VGASASDGSV CVLDLRK
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Molecular Weight
62.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TBL1X (Tobacco etch virus protease-like protein 1) is a member of the TBL protein family, which plays a pivotal role in various cellular processes, including signal transduction, gene regulation, and cellular proliferation. Research on TBL1X has gained momentum due to its potential implications in cancer biology, where dysregulation of the protein has been linked to tumorigenesis and metastasis. The protein functions as a co-regulator of nuclear receptors and interacting partners, highlighting its significance in transcriptional regulation. Understanding the structure and function of TBL1X can provide valuable insights into its role in health and disease. In the context of therapeutic interventions, TBL1X has emerged as a promising target for novel cancer treatments, given its involvement in key signaling pathways. The recombinant production of TBL1X has paved the way for detailed functional assays and crystallographic studies, aimed at elucidating its mechanism of action and interactions at the molecular level. Advances in this research are expected to contribute to the development of targeted therapies and enhance our understanding of protein function in various biological systems.
