Analytical Data
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Gene name
TBCCD1
- Application
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Alternative Names
TBCCD1; TBCC domain-containing protein 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NVR7
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Expression Region
1-557 aa
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AA Sequence
MDQSRVLLWV KAEPFIVGAL QVPPPSKFSL HYLRKISTYV QIRATEGAYP RLYWSTWRHI ACGKLQLAKD LAWLYFEIFD SLSMKTPEER LEWSEVLSNC MSEEEVEKQR NQLSVDTLQF LLFLYIQQLN KVSLRTSLIG EEWPSPRNKS QSPDLTEKSN CHNKNWNDYS HQAFVYDHLS DLLELLLDPK QLTASFHSTH SSLVSREAVV ALSFLIEGTI SRARKIYPLH ELALWQPLHA DSGFSKISKT FSFYKLETWL RSCLTGNPFG TSACLKSGKK LAWAHQVEGT TKRAKIACNT HVAPRMHRLV VMSQVYKQTL AKSSDTLAGA HVKIHRCNES FIYLLSPLRS VTIEKCRNSI FVLGPVGTTL HLHSCDNVKV IAVCHRLSIS STTGCIFHVL TPTRPLILSG NQTVTFAPFH THYPMLEDHM ARTGLATVPN YWDNPMVVCR ENSDTRVFQL LPPCEFYVFI IPFEMEGDTT EIPGGLPSVY QKALGQREQK IQIWQKTVKE AHLTKDQRKQ FQVLVENKFY EWLINTGHRQ QLDSLVPPAA GSKQAAG
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Molecular Weight
63.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TBCCD1, a member of the TBC (Tre-2/Bub2/Cepl) domain-containing proteins, has garnered significant interest in recent research due to its potential role in the regulation of cellular processes such as cell division, cytokinesis, and membrane trafficking. Its involvement in the Rab GTPase signaling pathways suggests a crucial function in vesicle transport and organelle dynamics, which are vital for maintaining cellular homeostasis. Studies indicate that TBCCD1 could be implicated in various diseases, including cancer, where altered cellular trafficking and division contribute to tumorigenesis. Furthermore, TBCCD1's structural features, including its TBC domain, provide insights into its enzymatic activity and interactions with partner proteins. As a result, characterizing TBCCD1 at the molecular level is essential for elucidating its biological functions and potential as a therapeutic target. Current research efforts are focused on understanding its mechanistic roles in cellular pathways and its overall impact on health and disease, paving the way for future studies aimed at leveraging TBCCD1 in biomedical applications.
