Analytical Data
-
Gene name
PDP
- Application
-
Alternative Names
PDP；PDP；PPM2C；[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1. mitochondrial
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9P0J1
-
Expression Region
1-537aa
-
AA Sequence
MPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCSSSYIPQSRLRYTPHPAYATFCRPKENWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNTGESTDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVTLGQMHGLLTERRTKMSSVFEDQNAATHLIRHAVGNNEFGTVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAYQNQE
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The study of PDP (Protein Disulfide Isomerase-like Protein) recombinant proteins has gained significant interest in the fields of molecular biology and biotechnology due to their crucial role in protein folding and maturation within cells. Protein disulfide isomerases, including PDPs, are essential enzymes that catalyze the formation and rearrangement of disulfide bonds during protein synthesis, ensuring the correct three-dimensional structure necessary for protein function. In various organisms, PDPs are implicated in critical physiological processes, such as cellular stress responses and the maintenance of protein homeostasis. With the rise of genetic engineering techniques, researchers have been able to produce recombinant PDPs, allowing for detailed studies of their mechanisms, functional roles, and interactions with other cellular components. Such investigations have profound implications for understanding diseases related to protein misfolding, such as Alzheimer’s and cystic fibrosis, where defective protein folding contributes to pathogenesis. Additionally, recombinant PDPs are explored for their potential applications in biopharmaceuticals, where enhancing protein stability and folding can improve the efficacy of therapeutic proteins. Thus, the research on PDP recombinant proteins not only enriches our fundamental understanding of cellular biology but also paves the way for innovative therapeutic strategies and biotechnological advancements.
