Analytical Data
-
基因名
TBC1D3B
- Application
-
别名
TBC1D3B; TBC1D3I; TBC1 domain family member 3B
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
A6NDS4
-
表达区间
1-549 aa
-
氨基酸序列
MDVVEVAGSW WAQEREDIIM KYEKGHRAGL PEDKGPKPFR SYNNNVDHLG IVHETELPPL TAREAKQIRR EISRKSKWVD MLGDWEKYKS SRKLIDRAYK GMPMNIRGPM WSVLLNIEEM KLKNPGRYQI MKEKGKRSSE HIQRIDRDIS GTLRKHMFFR DRYGTKQREL LHILLAYEEY NPEVGYCRDL SHIAALFLLY FPEEDAFWAL VQLLASERHS LQGFHSPNGG TVQGLQDQQE HVVATSQSKT MGHQDKKDLC GQCSPLGCLI RILIDGISLG LTLRLWDVYL VEGEQALMPI TRIAFKVQQK RLTKTSRCGP WARFCNRFVD TWARDEDTVL KHLRASMKKL TRKQGDLPPP AKPEQGSSAS RPVPASRGGK TLCKGDRQAP PGPPARFPRP IWSASPPRAP RSSTPCPGGA VREDTYPVGT QGVPSPALAQ GGPQGSWRFL QWNSMPRLPT DLDVEGPWFR HYDFRQSCWV RAISQEDQLA PCWQAEHPAE RVRSAFAAPS TDSDQGTPFR ARDEQQYAPT SGPCLCGLHL ESSQFPPGF
-
分子量
62.3 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TBC1D3B, a member of the TBC (Tre-2/Bub2/CDC16) domain family, has garnered significant interest in recent years due to its potential role in cellular processes such as vesicle trafficking and signaling pathways. This protein is primarily known for its involvement in regulating the small GTPase Rab proteins, which are critical for various intracellular transport mechanisms. Research has indicated that TBC1D3B may play a pivotal role in cancer biology, particularly in tumor progression and metastasis, positioning it as a potential biomarker and therapeutic target. Furthermore, the protein's interactions with various cellular components suggest its involvement in essential biological functions, including autophagy and endocytosis. However, the specific molecular mechanisms through which TBC1D3B exerts its effects remain poorly understood, necessitating further investigation. Studies focusing on the recombinant expression of TBC1D3B are crucial for elucidating its structure-function relationship, enabling a deeper understanding of its biological roles. By generating and characterizing recombinant TBC1D3B, researchers aim to explore its biochemical properties and establish its significance in both normal physiology and pathological conditions. This research not only contributes to our knowledge of TBC1D3B itself but also opens up avenues for developing novel therapeutic strategies that target its functions in disease settings, particularly in cancer treatment.
