Analytical Data
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基因名
C1qL1
- Application
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别名
C1qL1;CTRP11;Complement C1q-like Protein 4
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O75973
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表达区间
1-258aa
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氨基酸序列
MLLVLVVLIPVLVSSGGPEGHYEMLGTCRMVCDPYPARGPGAGARTDGGD ALSEQSGAPPPSTLVQGPQGKPGRTGKPGPPGPPGDPGPPGPVGPPGEKG EPGKPGPPGLPGAGGSGAISTATYTTVPRVAFYAGLKNPHEGYEVLKFDD VVTNLGNNYDAASGKFTCNIPGTYFFTYHVLMRGGDGTSMWADLCKNGQV RASAIAQDADQNYDYASNSVILHLDAGDEVFIKLDGGKAHGGNSNKYSTF SGFIIYSD
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
C1qL1, a member of the complement system, has garnered attention in recent years due to its crucial role in immune response and its potential implications in various diseases, including autoimmune disorders and cancer. Functioning as a ligand for C1q, C1qL1 is involved in the regulation of phagocytosis and inflammation, acting as a bridge between innate and adaptive immunity. Research has revealed that C1qL1 influences the activation of immune cells and modulates their responses, highlighting its significance in immune homeostasis. Additionally, aberrant expression of C1qL1 has been implicated in pathological conditions, prompting investigations into its potential as a biomarker and therapeutic target. Studies focusing on the structural and functional characterization of C1qL1 recombinant proteins are crucial for understanding their interactions with various immune components and their mechanistic roles in disease pathways. By elucidating the role of C1qL1 in the complement system, researchers aim to pave the way for novel immunotherapeutic strategies and enhance our understanding of immune regulation, particularly in contexts where traditional therapies have been ineffective.












