Analytical Data
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Gene name
WSCD1
- Application
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Alternative Names
WSCD1; KIAA0523; WSC domain-containing Protein 1
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q658N2
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Expression Region
1-575 aa
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AA Sequence
MAKPFFRLQKFLRRTQFLLFFLTAAYLMTGSLLLLQRVRVALPQGPRAPGPLQTLPVAAVALGVGLLDSRALHDPRVSPELLLGVDMLQSPLTRPRPGPRWLRSRNSELRQLRRRWFHHFMSDSQGPPALGPEAARPAIHSRGTYIGCFSDDGHERTLKGAVFYDLRKMTVSHCQDACAERSYVYAGLEAGAECYCGNRLPAVSVGLEECNYECKGEKGSVCGAVDRLSVYRVDELQPGSRKRRTATYRGCFRLPENITHAFPSSLIQANVTVGTCSGFCSQKEFPLAILRGWECYCAYPTPRFNLRDAMDSSVCGQDPEAQRLAEYCEVYQTPVQDTRCTDRRFLPNKSKVFVALSSFPGAGNTWARHLIEHATGFYTGSYYFDGTLYNKGFKGEKDHWRSRRTICVKTHESGRREIEMFDSAILLIRNPYRSLVAEFNRKCAGHLGYAADRNWKSKEWPDFVNSYASWWSSHVLDWLKYGKRLLVVHYEELRRSLVPTLREMVAFLNVSVSEERLLCVENNKEGSFRRRGRRSHDPEPFTPEMKDLINGYIRTVDQALRDHNWTGLPREYVPR
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Molecular Weight
92.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
WSCD1, or WASH complex subunit, is a protein that plays a crucial role in various cellular processes, particularly in the regulation of the actin cytoskeleton and endocytic pathways. Research on WSCD1 has gained significant attention due to its involvement in cellular mechanisms that are fundamental to cell motility, division, and signaling. The WASH complex, of which WSCD1 is a key component, is essential for maintaining cellular homeostasis by facilitating the recycling of membrane proteins and the removal of damaged organelles. Abnormalities in WSCD1 function have been implicated in several diseases, including cancer and neurodegenerative disorders, highlighting its potential as a therapeutic target. The study of WSCD1 as a recombinant protein provides insights into its structural and functional characteristics, enabling researchers to explore its interactions with other cellular components. Additionally, the production of WSCD1 as a recombinant protein allows for high-throughput screening and functional assays, which are crucial for understanding its role in cellular dynamics and for developing potential interventions in diseases associated with its dysregulation. The ongoing research aims to elucidate the precise mechanisms by which WSCD1 influences cell behavior and to leverage this knowledge for the development of new therapeutic strategies.
