Cat: PAX2000-11836

Recombinant Human TAX1BP1 Protein,His

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Analytical Data

  • Gene name

    TAX1BP1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    1200003J11Rik; 1700069J21Rik; Aa1076; AA930106; CALCOCO 3; CALCOCO3; D6Ertd404e; D6Ertd772e; Human T cell leukemia virus type 1-binding protein; Liver regeneration-related protein LRRG004; MGC94031; PRO0105; T6BP; Tax1 (human T cell leukemia virus type I) binding protein; Tax1 (human T cell leukemia virus type I) binding protein 1; Tax1 binding protein 1; Tax1 binding protein; Tax1-binding protein 1; Tax1-binding protein 1 homolog; TAX1BP1; TAX1BP1 protein; tax1bp1b; TAXB1_HUMAN; TRAF 6 binding protein; TRAF6 binding protein; TRAF6 binding protein T6BP; TRAF6-binding protein; TRAF6-interacting protein; TXBP 151; TXBP151; wu:fc20c12; wu:fc56e11; zgc:73219; zgc:77129

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q86VP1

  • Expression Region

    1-789 aa

  • AA Sequence

    MTSFQEVPLQ TSNFAHVIFQ NVAKSYLPNA HLECHYTLTP YIHPHPKDWV GIFKVGWSTA RDYYTFLWSP MPEHYVEGST VNCVLAFQGY YLPNDDGEFY QFCYVTHKGE IRGASTPFQF RASSPVEELL TMEDEGNSDM LVVTTKAGLL ELKIEKTMKE KEELLKLIAV LEKETAQLRE QVGRMERELN HEKERCDQLQ AEQKGLTEVT QSLKMENEEF KKRFSDATSK AHQLEEDIVS VTHKAIEKET ELDSLKDKLK KAQHEREQLE CQLKTEKDEK ELYKVHLKNT EIENTKLMSE VQTLKNLDGN KESVITHFKE EIGRLQLCLA EKENLQRTFL LTTSSKEDTC FLKEQLRKAE EQVQATRQEV VFLAKELSDA VNVRDRTMAD LHTARLENEK VKKQLADAVA ELKLNAMKKD QDKTDTLEHE LRREVEDLKL RLQMAADHYK EKFKECQRLQ KQINKLSDQS ANNNNVFTKK TGNQQKVNDA SVNTDPATSA STVDVKPSPS AAEADFDIVT KGQVCEMTKE IADKTEKYNK CKQLLQDEKA KCNKYADELA KMELKWKEQV KIAENVKLEL AEVQDNYKEL KRSLENPAER KMEGQNSQSP QCFKTCSEQN GYVLTLSNAQ PVLQYGNPYA SQETRDGADG AFYPDEIQRP PVRVPSWGLE DNVVCSQPAR NFSRPDGLED SEDSKEDENV PTAPDPPSQH LRGHGTGFCF DSSFDVHKKC PLCELMFPPN YDQSKFEEHV ESHWKVCPMC SEQFPPDYDQ QVFERHVQTH FDQNVLNFD

  • Molecular Weight

    90.8 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

TAX1BP1 (Tax1-binding protein 1) is a cellular protein that plays a crucial role in the regulation of various cellular processes, including apoptosis, immune response, and signal transduction. It is particularly known for its involvement in the cellular response to viral infections and has been studied in the context of human immunodeficiency virus (HIV) infection, where it acts as a host factor that can influence viral replication. The protein contains specific domains that facilitate interactions with other cellular proteins, thereby modulating signaling pathways that are essential for maintaining cellular homeostasis. Recent studies have highlighted the significance of TAX1BP1 in both oncogenesis and viral pathogenesis, making it a target of interest for therapeutic interventions. Moreover, recombinant forms of TAX1BP1 have been utilized in experimental research to elucidate its functional roles, structure, and interactions at the molecular level. Understanding the biological functions and mechanisms of TAX1BP1 may provide insights into developing novel strategies for treating viral infections and certain types of cancer, thus underscoring its relevance in medical research.

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