Cat: PAX2000-11832

Recombinant Human TAS2R5 Protein,GST

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Analytical Data

  • Gene name

    TAS2R5

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    TAS2R5; Taste receptor type 2 member 5; T2R5

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9NYW4

  • AA Sequence

    MLSAGLGLLMLVAVVEFLIGLIGNGSLVVWSFREWIRKFNWSSYNLIILGLAGCRFLLQWLIILDLSLFPLFQSSRWLRYLSIFWVLVSQASLWFATFLSVFYCKKITTFDRPAYLWLKQRAYNLSLWCLLGYFIINLLLTVQIGLTFYHPPQGNSSIRYPFESWQYLYAFQLNSGSYLPLVVFLVSSGMLIVSLYTHHKKMKVHSAGRRDVRAKAHITALKSLGCFLLLHLVYIMASPFSITSKTYPPDLTSVFIWETLMAAYPSLHSLILIMGIPRVKQTCQKILWKAVCARRCWGP

  • Molecular Weight

    34.5 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

TAS2R5 is a member of the type 2 taste receptor family, which plays a significant role in the perception of bitter tastes in humans and other mammals. The study of TAS2R5 has gained interest due to its potential implications in nutrition, pharmacology, and toxicology, as bitter taste perception is closely linked to the avoidance of harmful substances, many of which are bitter in taste. Recent research has shown that TAS2R5 is not only involved in taste perception but may also have functions beyond the gustatory system, including roles in physiological responses and signaling pathways associated with aversion and protective responses to harmful compounds. The expression and functional characterization of TAS2R5 recombinant proteins provide critical insights into its ligand-binding properties and mechanisms of action, contributing to a better understanding of bitter taste signaling and its evolutionary significance. Moreover, elucidating the structure and function of TAS2R5 could have broader implications in designing better flavoring agents, therapeutics, and understanding taste disorders. Overall, the study of TAS2R5 recombinant proteins is vital for advancing our knowledge of taste perception and its implications in health and disease.

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