Analytical Data
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Gene name
TAS2R43
- Application
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Alternative Names
TAS2R43; Taste receptor type 2 member 43; T2R43; Taste receptor type 2 member 52; T2R52
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P59537
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Expression Region
1-309 aa
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AA Sequence
MITFLPIIFSSLVVVTFVIGNFANGFIALVNSIESFKRQKISFADQILTALAVSRVGLLWVLLLNWYSTVLNPAFNSVEVRTTAYNIWAVINHFSNWLATTLSIFYLLKIANFSNFIFLHLKRRVKSVILVMLLGPLLFLACHLFVINMNEIVRTKEFEGNMTWKIKLKSAMYFSNMTVTMVANLVPFTLTLLSFMLLICSLCKHLKKMQLRGKGSQDPSTKVHIKALQTVISFLLLCAIYFLSIMISVWSFGSLENKPVFMFCKAIRFSYPSIHPFILIWGNKKLKQTFLSVFWQMRYWVKGEKTSSP
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Molecular Weight
61.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TAS2R43, part of the bitter taste receptor gene family, has garnered significant interest in the field of sensory biology and pharmacology due to its role in detecting bitter compounds, which can influence dietary choices and behaviors. Research surrounding TAS2R43 is crucial for understanding how humans perceive bitterness and how this perception affects food selection and ingestion. This receptor is particularly notable for its potential link to various physiological processes, including those related to toxic compound detection, metabolic regulation, and overall taste perception. Given the evolutionary significance of taste receptors in survival, studies on TAS2R43 can also provide insights into how taste perception has adapted in response to environmental pressures. Furthermore, the exploration of TAS2R43's signal transduction pathways may have implications in developing new therapeutic strategies for conditions such as obesity and diabetes, as altered taste perception can directly impact dietary habits. The production of recombinant TAS2R43 protein enables researchers to investigate its molecular characteristics and functional interactions in vitro, facilitating a more comprehensive understanding of its roles and applications in both basic and applied sciences. Thus, ongoing research on TAS2R43 aims to elucidate its complexities and harness its potential benefits in health and nutrition.
