Analytical Data
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Gene name
WDR59
- Application
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Alternative Names
WDR59; KIAA1923; FP977; GATOR complex Protein WDR59; WD repeat-containing Protein 59
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6PJI9
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Expression Region
1-571 aa
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AA Sequence
MAARWSSENVVVEFRDSQATAMSVDCLGQHAVLSGRRFLYIVNLDAPFEGHRKISRQSKWDIGAVQWNPHDSFAHYFAASSNQRVDLYKWKDGSGEVGTTLQGHTRVISDLDWAVFEPDLLVTSSVDTYIYIWDIKDTRKPTVALSAVAGASQVKWNKKNANCLATSHDGDVRIWDKRKPSTAVEYLAAHLSKIHGLDWHPDSEHILATSSQDNSVKFWDYRQPRKYLNILPCQVPVWKARYTPFSNGLVTVMVPQLRRENSLLLWNVFDLNTPVHTFVGHDDVVLEFQWRKQKEGSKDYQLVTWSRDQTLRMWRVDSQMQRLCANDILDGVDEFIESISLLPEPEKTLHTEDTDHQHTASHGEEEALKEDPPRNLLEERKSDQLGLPQTLQQEFSLINVQIRNVNVEMDAADRSCTVSVHCSNHRVKMLVKFPAQYPNNAAPSFQFINPTTITSTMKAKLLKILKDTALQKVKRGQSCLEPCLRQLVSCLESFVNQEDSASSNPFALPNSVTPPLPTFARVTTAYGSYQDANIPFPRTSGARFCGAGYLVYFTRPMTMHRAVSPTEPTPR
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Molecular Weight
91.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
WDR59, or WD repeat domain 59, is a protein that has garnered interest due to its potential involvement in various cellular processes, including cell proliferation and differentiation. It is characterized by the presence of multiple WD repeats, which are structural motifs that facilitate protein-protein interactions. Recent studies have suggested that WDR59 may play a significant role in the regulation of the cell cycle and in maintaining genomic stability. Abnormal expression or mutation of WDR59 has been implicated in several diseases, including certain cancers, highlighting its potential as a biomarker or therapeutic target. Research on recombinant WDR59 proteins aims to elucidate the functional mechanisms of this protein and its interactions with other cellular components. By producing WDR59 in a recombinant system, researchers can obtain pure protein for biochemical assays, structural studies, and functional assays, allowing for a deeper understanding of its role in health and disease. As the scientific community continues to explore the intricacies of cellular functions, WDR59 stands out as a protein of interest, with the potential to provide insights into novel therapeutic strategies.
