Analytical Data
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Gene name
WDR58
- Application
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Alternative Names
THOC6; WDR58; PSEC0006; THO complex subunit 6 homolog; Functional spliceosome-associated Protein 35; fSAP35; WD repeat-containing Protein 58
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q86W42
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Expression Region
1-341 aa
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AA Sequence
MERAVPLAVP LGQTEVFQAL QRLHMTIFSQ SVSPCGKFLA AGNNYGQIAI FSLSSALSSE AKEESKKPVV TFQAHDGPVY SMVSTDRHLL SAGDGEVKAW LWAEMLKKGC KELWRRQPPY RTSLEVPEIN ALLLVPKENS LILAGGDCQL HTMDLETGTF TRVLRGHTDY IHCLALRERS PEVLSGGEDG AVRLWDLRTA KEVQTIEVYK HEECSRPHNG RWIGCLATDS DWMVCGGGPA LTLWHLRSST PTTIFPIRAP QKHVTFYQDL ILSAGQGRCV NQWQLSGELK AQVPGSSPGL LSLSLNQQPA APECKVLTAA GNSCRVDVFT NLGYRAFSLS F
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Molecular Weight
37.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
WDR58 (WD Repeat Domain 58) is a protein that has gained attention in recent years due to its potential roles in cellular processes, including cell proliferation, apoptosis, and DNA damage response. It is characterized by the presence of WD repeats, which are structural motifs often involved in protein-protein interactions, suggesting that WDR58 could function as a scaffold or regulatory molecule in various cellular pathways. Research has indicated that mutations or dysregulation of WDR58 may be implicated in several diseases, including cancer and neurological disorders. The study of recombinant WDR58 protein is crucial for elucidating its biological functions and mechanisms of action. By producing WDR58 in a recombinant form, researchers can investigate its biochemical properties, interactions with other proteins, and effects on cellular signaling pathways. Additionally, understanding WDR58's role in disease may uncover novel therapeutic targets or diagnostic markers. Overall, the investigation of recombinant WDR58 protein is a significant step towards understanding its contributions to cellular homeostasis and its potential implications in human health and disease.
