Analytical Data
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基因名
WDR53
- Application
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别名
WDR53WD repeat-containing Protein 53
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q7Z5U6
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表达区间
1-358 aa
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氨基酸序列
MAVKWTGGHS SPVLCLNASK EGLLASGAEG GDLTAWGEDG TPLGHTRFQG ADDVTSVLFS PSCPTKLYAS HGETISVLDV RSLKDSLDHF HVNEEEINCL SLNQTENLLA SADDSGAIKI LDLENKKVIR SLKRHSNICS SVAFRPQRPQ SLVSCGLDMQ VMLWSLQKAR PLWITNLQED ETEEMEGPQS PGQLLNPALA HSISVASCGN IFSCGAEDGK VRIFRVMGVK CEQELGFKGH TSGVSQVCFL PESYLLLTGG NDGKITLWDA NSEVEKKQKS PTKRTHRKKP KRGTCTKQGG NTNASVTDEE EHGNILPKLN IEHGEKVNWL LGTKIKGHQN ILVADQTSCI SVYPLNEF
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分子量
38.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
WDR53, also known as WD repeat domain 53, is a protein implicated in various cellular processes, including stress response, cell cycle regulation, and gene expression. It belongs to a family of proteins characterized by the presence of WD repeat motifs, which are involved in facilitating protein-protein interactions. The precise biological function of WDR53 has remained somewhat elusive, leading researchers to explore its potential roles in different cellular contexts. Recent studies suggest that WDR53 may play a significant role in the cellular response to DNA damage and stress, indicating its importance in maintaining genomic stability and promoting cell survival under adverse conditions. Additionally, dysregulation of WDR53 has been implicated in various diseases, including cancer, making it a target of interest for therapeutic interventions. The production of recombinant WDR53 protein allows for detailed biochemical studies and functional assays, enabling researchers to investigate its molecular mechanisms and interactions with other cellular components. Understanding the role of WDR53 in cell biology not only contributes to the basic understanding of cellular mechanisms but also holds potential implications for the development of novel therapeutic strategies in diseases where WDR53 is involved. As such, research on recombinant WDR53 is positioned at the intersection of fundamental biology and translational medicine, highlighting its significance in both scientific inquiry and potential clinical applications.
