Analytical Data
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Gene name
WDR42A
- Application
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Alternative Names
DDB1- and CUL4-associated factor 8. WD repeat-containing Protein 42A
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q5TAQ9
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Expression Region
1-273 aa
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AA Sequence
MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTETESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSDDERALEDWVSSETSALPRPRWQALPALRERELGSSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQVRQGSIIATERIRHELEKSELQHGLGADSELL
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Molecular Weight
55.77 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
WDR42A, a member of the WD40 repeat protein family, has garnered interest due to its potential roles in various cellular processes, including the regulation of protein interactions and involvement in cellular signaling pathways. Research into WDR42A has highlighted its potential implications in human diseases, particularly in cancer and neurodegenerative disorders. The protein's structure, characterized by multiple WD repeats, suggests a functional role in modulating protein complexes and facilitating molecular interactions. Recent studies have aimed to elucidate the precise mechanisms by which WDR42A exerts its effects within the cell, including its influence on gene expression and cellular stress responses. Furthermore, the generation of recombinant WDR42A protein provides a valuable tool for understanding its biochemical properties and interactions with other cellular components. By employing techniques such as co-immunoprecipitation and mass spectrometry, researchers are beginning to map the interaction networks involving WDR42A, which may offer insights into its functional roles and therapeutic potential. Overall, the exploration of WDR42A through recombinant protein studies is essential for uncovering its significance in health and disease, making it a promising target for future research endeavors.
