Analytical Data
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Gene name
PABPC1L
- Application
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Alternative Names
PABPC1L；C20orf119；Polyadenylate-binding Protein 1-like
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q4VXU2
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Expression Region
1-614aa
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AA Sequence
MNASGSGYPL ASLYVGDLHP DVTEAMLYEK FSPAGPILSI RVCRDVATRR SLGYAYINFQ QPADAERALD TMNFEMLKGQ PIRIMWSQRD PGLRKSGVGN IFIKNLEDSI DNKALYDTFS TFGNILSCKV ACDEHGSRGF GFVHFETHEA AQQAINTMNG MLLNDRKVFV GHFKSRRERE AELGARALEF TNIYVKNLPV DVDEQGLQDL FSQFGKMLSV KVMRDNSGHS RCFGFVNFEK HEEAQKAVVH MNGKEVSGRL LYAGRAQKRV ERQNELKRRF EQMKQDRLRR YQGVNLYVKN LDDSIDDDKL RKEFSPYGVI TSAKVMTEGG HSKGFGFVCF SSPEEATKAV TEMNGRIVGT KPLYVALAQR KEERKAILTN QYMQRLSTMR TLSNPLLGSF QQPSSYFLPA MPQPPAQAAY YGCGPVTPTQ PAPRWTSQPP RPSCASMVRP PVVPRRPPAH ISSVRQASTQ VPRTVPHTQR VANIGTQTTG PSGVGCCTPG RPLLPCKCSS AAHSTYRVQE PAVHIPGQEP LTASMLAAAP LHEQKQMIGE RLYPLIHDVH TQLAGKITGM LLEIDNSELL LMLESPESLH AKIDEAVAVL QAHQAMEQPK AYMH
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PABPC1L, or Poly(A) Binding Protein Cytoplasmic 1 Like, is a member of the poly(A)-binding protein family, which plays a crucial role in mRNA stability, transport, and translation regulation. Understanding PABPC1L is essential, as it is implicated in various cellular processes, including gene expression control and response to stress. Recent studies have indicated its involvement in key biological pathways, such as neurogenesis and inflammation, which may link it to certain diseases and developmental disorders. The expression patterns of PABPC1L suggest that it might serve as a regulatory factor in different tissues, including the nervous system, highlighting its potential significance in both normal physiology and pathological conditions. Research on recombinant PABPC1L protein is vital for elucidating its structure-function relationships, as well as for understanding its interactions with other cellular components, such as RNA and proteins. By generating and characterizing recombinant PABPC1L, scientists aim to uncover its functional mechanisms and explore its roles in cellular processes. This knowledge could pave the way for novel therapeutic strategies targeting diseases where PABPC1L is implicated, thereby contributing to advancements in biomedical research and potential clinical applications.
