Analytical Data
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基因名
SURF6
- Application
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别名
SURF-6; surf6; SURF6_HUMAN; Surfeit locus protein 6
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O75683
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表达区间
1-361 aa
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氨基酸序列
MASLLAKDAY LQSLAKKICS HSAPEQQART RAGKTQGSET AGPPKKKRKK TQKKFRKREE KAAEHKAKSL GEKSPAASGA RRPEAAKEEA AWASSSAGNP ADGLATEPES VFALDVLRQR LHEKIQEARG QGSAKELSPA ALEKRRRRKQ ERDRKKRKRK ELRAKEKARK AEEATEAQEV VEATPEGACT EPREPPGLIF NKVEVSEDEP ASKAQRRKEK RQRVKGNLTP LTGRNYRQLL ERLQARQSRL DELRGQDEGK AQELEAKMKW TNLLYKAEGV KIRDDERLLQ EALKRKEKRR AQRQRRWEKR TAGVVEKMQQ RQDRRRQNLR RKKAARAERR LLRARKKGRI LPQDLERAGL V
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分子量
41.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SURF6 is a highly conserved protein that plays a crucial role in ribosome biogenesis and the assembly of ribosomal RNA and proteins into functional ribosomes. Initially identified in studies related to cell growth and proliferation, SURF6 has garnered interest due to its potential involvement in various cellular processes and diseases, including cancer. Research has shown that SURF6 interacts with several key ribosomal and non-ribosomal proteins, suggesting it may serve as a regulatory factor in the ribosome assembly pathway. Additionally, aberrations in SURF6 expression and function have been correlated with various malignancies, leading to investigations into its role as a potential biomarker or therapeutic target. The focus of recent studies has centered on elucidating the mechanism by which SURF6 contributes to ribosome biogenesis and its influence on cellular stress responses. Understanding SURF6's function could provide insights into the fundamental molecular mechanisms underlying translation and protein synthesis, as well as reveal novel pathways that may be exploited for therapeutic intervention in diseases characterized by dysregulated protein synthesis. Thus, the ongoing research on SURF6 recombinant protein is not only significant for fundamental biology but also for its implications in disease mechanisms and potential treatments.
