Analytical Data
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Gene name
WDR20
- Application
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Alternative Names
WDR20WD repeat-containing Protein 20; Protein DMR
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8TBZ3
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Expression Region
2-569 aa
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AA Sequence
ATEGGGKEM NEIKTQFTTR EGLYKLLPHS EYSRPNRVPF NSQGSNPVRV SFVNLNDQSG NGDRLCFNVG RELYFYIYKG VRKAADLSKP IDKRIYKGTQ PTCHDFNHLT ATAESVSLLV GFSAGQVQLI DPIKKETSKL FNEERLIDKS RVTCVKWVPG SESLFLVAHS SGNMYLYNVE HTCGTTAPHY QLLKQGESFA VHTCKSKSTR NPLLKWTVGE GALNEFAFSP DGKFLACVSQ DGFLRVFNFD SVELHGTMKS YFGGLLCVCW SPDGKYIVTG GEDDLVTVWS FVDCRVIARG HGHKSWVSVV AFDPYTTSVE EGDPMEFSGS DEDFQDLLHF GRDRANSTQS RLSKRNSTDS RPVSVTYRFG SVGQDTQLCL WDLTEDILFP HQPLSRARTH TNVMNATSPP AGSNGNSVTT PGNSVPPPLP RSNSLPHSAV SNAGSKSSVM DGAIASGVSK FATLSLHDRK ERHHEKDHKR NHSMGHISSK SSDKLNLVTK TKTDPAKTLG TPLCPRMEDV PLLEPLICKK IAHERLTVLI FLEDCIVTAC QEGFICTWGR PGKVVSFNP
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Molecular Weight
62.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
WDR20 (WD repeat domain 20) is a protein that plays a crucial role in various cellular processes, including gene regulation, signal transduction, and cell cycle control. It contains WD repeats, which are beta-propeller structures known to facilitate protein-protein interactions, thus influencing protein complexes involved in these biological functions. Research into WDR20 has gained traction due to its potential implications in human diseases, particularly cancer and neurodevelopmental disorders. Studies have suggested that mutations or alterations in the expression of WDR20 may disrupt normal cellular functions and contribute to disease pathology. Furthermore, understanding the functional mechanisms of WDR20 is essential for identifying its role in critical pathways and exploring its potential as a therapeutic target. Scientists are employing techniques such as gene editing, RNA sequencing, and protein interaction assays to elucidate the comprehensive role of WDR20 in cellular scenarios. The continued investigation into the structure-function relationship of WDR20 could provide significant insights into its biological significance and pave the way for novel interventions aimed at modulating its activity in various diseases.
