Analytical Data
-
Gene name
SULT1C3
- Application
-
Alternative Names
SULT1C3; Sulfotransferase 1C3; ST1C3; EC 2.8.2.2
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q6IMI6
-
Expression Region
1-304 aa
-
AA Sequence
MAKIEKNAPT MEKKPELFNI MEVDGVPTLI LSKEWWEKVC NFQAKPDDLI LATYPKSGTT WMHEILDMIL NDGDVEKCKR AQTLDRHAFL ELKFPHKEKP DLEFVLEMSS PQLIKTHLPS HLIPPSIWKE NCKIVYVARN PKDCLVSYYH FHRMASFMPD PQNLEEFYEK FMSGKVVGGS WFDHVKGWWA AKDMHRILYL FYEDIKKDPK REIEKILKFL EKDISEEILN KIIYHTSFDV MKQNPMTNYT TLPTSIMDHS ISPFMRKGMP GDWKNYFTVA QNEEFDKDYQ KKMAGSTLTF RTEI
-
Molecular Weight
35.8 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SULT1C3, a member of the sulfotransferase family, plays a crucial role in the biotransformation of various endogenous and exogenous compounds through the process of sulfonation, which generally enhances their solubility and facilitates their excretion. This enzyme is particularly important in the metabolism of steroid hormones, neurotransmitters, and certain drugs, thereby influencing pharmacokinetics and toxicology. Research into SULT1C3 has intensified due to its potential implications in drug metabolism and individual variations in drug response, which can lead to adverse drug reactions or ineffective treatments. The recombinant expression of SULT1C3 protein is vital for understanding its biochemical properties, substrate specificity, and catalytic mechanisms. Furthermore, studying the structural characteristics of the SULT1C3 protein through crystallography and other biophysical methods can provide insights into its functional roles in different physiological contexts. Additionally, the investigation of polymorphisms and regulatory mechanisms that affect SULT1C3 expression may offer valuable information regarding interindividual variability in drug metabolism. Overall, the exploration of SULT1C3 recombinant protein not only contributes to our understanding of pharmacogenomics but also has the potential to inform the development of new therapeutic strategies tailored to individual metabolic profiles.
