Analytical Data
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基因名
STYK1
- Application
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别名
STYK1; NOK; Tyrosine-protein kinase STYK1; Novel oncogene with kinase domain; Protein PK-unique; Serine/threonine/tyrosine kinase 1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6J9G0
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表达区间
1-422 aa
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氨基酸序列
MGMTRMLLECSLSDKLCVIQEKQYEVIIVPTLLVTIFLILLGVILWLFIREQRTQQQRSGPQGIAPVPPPRDLSWEAGHGGNVALPLKETSVENFLGATTPALAKLQVPREQLSEVLEQICSGSCGPIFRANMNTGDPSKPKSVILKALKEPAGLHEVQDFLGRIQFHQYLGKHKNLVQLEGCCTEKLPLYMVLEDVAQGDLLGFLWTCRRDVMTMDGLLYDLTEKQVYHIGKQVLLALEFLQEKHLFHGDVAARNILMQSDLTAKLCGLGLAYEVYTRGAISSTQTIPLKWLAPERLLLRPASIRADVWSFGILLYEMVTLGAPPYPEVPPTSILEHLQRRKIMKRPSSCTHTMYSIMKSCWRWREADRPSPRELRLRLEAAIKTADDEAVLQVPELVVPELYAAVAGIRVESLFYNYSML
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分子量
73.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
STYK1, also known as serine/threonine kinase 1, has emerged as a significant focus in cancer research due to its involvement in various cellular processes, including cell proliferation, differentiation, and apoptosis. Abnormal expression of STYK1 has been associated with several types of malignancies, which suggests its potential role as a biomarker for cancer progression and prognosis. Recent studies have illustrated that STYK1 functions as a signaling molecule that can modulate key pathways involved in tumorigenesis, notably the MAPK/ERK and PI3K/AKT pathways, thereby influencing cell cycle regulation and survival mechanisms in cancer cells. Furthermore, the overexpression of STYK1 has been linked to enhanced metastatic potential and resistance to therapeutic interventions, underscoring its importance in cancer biology. As a result, the development of STYK1 recombinant proteins has become a vital area of research, aiming to elucidate its precise biological functions and molecular mechanisms. These recombinant proteins can serve as valuable tools in dissecting the signaling pathways mediated by STYK1, aiding in the identification of potential therapeutic targets. Additionally, understanding STYK1’s interactions with other proteins within the cellular framework can provide insights into its role in disease progression, potentially leading to innovative approaches for cancer treatment and management. Overall, the study of STYK1 through recombinant protein technology holds promise not only for elucidating fundamental biological processes but also for advancing clinical applications in oncology.
