Analytical Data
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Gene name
WBSCR16
- Application
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Alternative Names
5730496C04Rik; AU019812; DKFZp434D0421; MGC189739; MGC44931; RCC1-like G exchanging factor-like Protein; WBS16_HUMAN; Wbscr16; Williams-Beuren syndrome chromosomal region 16 Protein
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96I51
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Expression Region
1-464 aa
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AA Sequence
MALVALVAGA RLGRRLSGPG LGRGHWTAAR RSRSRREAAE AEAEVPVVQY VGERAARADR VFVWGFSFSG ALGVPSFVVP SSGPGPRAGA RPRRRIQPVP YRLELDQKIS SAACGYGFTL LSSKTADVTK VWGMGLNKDS QLGFHRSRKD KTRGYEYVLE PSPVSLPLDR PQETRVLQVS CGRAHSLVLT DREGVFSMGN NSYGQCGRKV VENEIYSESH RVHRMQDFDG QVVQVACGQD HSLFLTDKGE VYSCGWGADG QTGLGHYNIT SSPTKLGGDL AGVNVIQVAT YGDCCLAVSA DGGLFGWGNS EYLQLASVTD STQVNVPRCL HFSGVGKVRQ AACGGTGCAV LNGEGHVFVW GYGILGKGPN LVESAVPEMI PPTLFGLTEF NPEIQVSRIR CGLSHFAALT NKGELFVWGK NIRGCLGIGR LEDQYFPWRV TMPGEPVDVA CGVDHMVTLA KSFI
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Molecular Weight
49.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The WBSCR16 protein, associated with Williams-Beuren syndrome (WBS), has garnered attention due to its potential role in neurodevelopment and cardiovascular health. WBS is a genetic disorder caused by a deletion of genetic material on chromosome 7, leading to a range of developmental, cognitive, and cardiovascular issues. WBSCR16, located within this deletion region, is hypothesized to play a significant role in the expression and regulation of genes related to these aspects. Research into WBSCR16 involves understanding its structure, function, and interaction with other proteins, which could provide insights into the molecular mechanisms underlying WBS. Studies suggest that alterations in WBSCR16 may contribute to the clinical manifestations observed in individuals with the syndrome, making it a focal point for both basic research and potential therapeutic interventions. Investigating the recombinant form of WBSCR16 enables researchers to delve deeper into its functional properties, paving the way for advancements in gene therapy and personalized medicine targeted at ameliorating the effects of Williams-Beuren syndrome.
