Analytical Data
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基因名
STXBP4
- Application
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别名
FLJ16496; MGC149829; MGC50337; OTTHUMP00000082667; OTTHUMP00000227400; STX4-interacting protein; STXB4_HUMAN; Stxbp4; Synip; Syntaxin 4 interacting protein; Syntaxin 4-interacting protein; Syntaxin binding protein 4; Syntaxin-binding protein 4
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6ZWJ1
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表达区间
1-553 aa
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氨基酸序列
MNKNTSTVVS PSLLEKDPAF QMITIAKETG LGLKVLGGIN RNEGPLVYIQ EIIPGGDCYK DGRLKPGDQL VSVNKESMIG VSFEEAKSII TGAKLRLESA WEIAFIRQKS DNIQPENLSC TSLIEASGEY GPQASTLSLF SSPPEILIPK TSSTPKTNND ILSSCEIKTG YNKTVQIPIT SENSTVGLSN TDVASAWTEN YGLQEKISLN PSVRFKAEKL EMALNYLGIQ PTKEQHQALR QQVQADSKGT VSFGDFVQVA RNLFCLQLDE VNVGAHEISN ILDSQLLPCD SSEADEMERL KCERDDALKE VNTLKEKLLE SDKQRKQLTE ELQNVKQEAK AVVEETRALR SRIHLAEAAQ RQAHGMEMDY EEVIRLLEAK ITELKAQLAD YSDQNKESVQ DLKKRIMVLD CQLRKSEMAR KTFEASTEKL LHFVEAIQEV FSDNSTPLSN LSERRAVLAS QTSLTPLGRN GRSIPATLAL ESKELVKSVR ALLDMDCLPY GWEEAYTADG IKYFINHVTQ TTSWIHPVMS VLNLSRSEEN EEDCSRELPN QKS
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分子量
61.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
STXBP4, or Syntaxin Binding Protein 4, is a member of the STXBP family and plays a crucial role in regulating exocytosis and synaptic transmission in neuronal and non-neuronal cells. It is primarily involved in the docking and fusion of synaptic vesicles with the plasma membrane, facilitating the release of neurotransmitters and other essential substances. Research has highlighted STXBP4's involvement in various physiological processes, including insulin secretion, neuronal communication, and immune responses. Additionally, dysregulation of STXBP4 has been implicated in several pathological conditions, such as diabetes, neurological disorders, and cancer. Given its vital role in numerous cellular functions, the study of STXBP4 recombinant proteins has garnered significant interest for developing therapeutic strategies targeting these diseases. Furthermore, the expression and characterization of STXBP4 recombinant proteins enable researchers to elucidate the protein's structure-function relationship, identify potential binding partners, and explore its mechanistic pathways in both health and disease. By understanding STXBP4's role at a molecular level, researchers aim to contribute to the development of novel interventions that may improve disease outcomes and enhance cellular function.
