Analytical Data
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Gene name
STXBP4
- Application
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Alternative Names
FLJ16496; MGC149829; MGC50337; OTTHUMP00000082667; OTTHUMP00000227400; STX4-interacting protein; STXB4_HUMAN; Stxbp4; Synip; Syntaxin 4 interacting protein; Syntaxin 4-interacting protein; Syntaxin binding protein 4; Syntaxin-binding protein 4
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6ZWJ1
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Expression Region
1-553 aa
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AA Sequence
MNKNTSTVVS PSLLEKDPAF QMITIAKETG LGLKVLGGIN RNEGPLVYIQ EIIPGGDCYK DGRLKPGDQL VSVNKESMIG VSFEEAKSII TGAKLRLESA WEIAFIRQKS DNIQPENLSC TSLIEASGEY GPQASTLSLF SSPPEILIPK TSSTPKTNND ILSSCEIKTG YNKTVQIPIT SENSTVGLSN TDVASAWTEN YGLQEKISLN PSVRFKAEKL EMALNYLGIQ PTKEQHQALR QQVQADSKGT VSFGDFVQVA RNLFCLQLDE VNVGAHEISN ILDSQLLPCD SSEADEMERL KCERDDALKE VNTLKEKLLE SDKQRKQLTE ELQNVKQEAK AVVEETRALR SRIHLAEAAQ RQAHGMEMDY EEVIRLLEAK ITELKAQLAD YSDQNKESVQ DLKKRIMVLD CQLRKSEMAR KTFEASTEKL LHFVEAIQEV FSDNSTPLSN LSERRAVLAS QTSLTPLGRN GRSIPATLAL ESKELVKSVR ALLDMDCLPY GWEEAYTADG IKYFINHVTQ TTSWIHPVMS VLNLSRSEEN EEDCSRELPN QKS
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Molecular Weight
61.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
STXBP4, or Syntaxin Binding Protein 4, is a member of the STXBP family and plays a crucial role in regulating exocytosis and synaptic transmission in neuronal and non-neuronal cells. It is primarily involved in the docking and fusion of synaptic vesicles with the plasma membrane, facilitating the release of neurotransmitters and other essential substances. Research has highlighted STXBP4's involvement in various physiological processes, including insulin secretion, neuronal communication, and immune responses. Additionally, dysregulation of STXBP4 has been implicated in several pathological conditions, such as diabetes, neurological disorders, and cancer. Given its vital role in numerous cellular functions, the study of STXBP4 recombinant proteins has garnered significant interest for developing therapeutic strategies targeting these diseases. Furthermore, the expression and characterization of STXBP4 recombinant proteins enable researchers to elucidate the protein's structure-function relationship, identify potential binding partners, and explore its mechanistic pathways in both health and disease. By understanding STXBP4's role at a molecular level, researchers aim to contribute to the development of novel interventions that may improve disease outcomes and enhance cellular function.
