Analytical Data
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Gene name
WBP11
- Application
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Alternative Names
DKFZp779M1063; MGC94547; Npw38 binding Protein; Npw38 binding Protein NpwBP; Npw38-binding Protein; NpwBP; PPP1R165; Protein phosphatase 1 regulatory subunit 165; SH3 domain binding Protein SNP70; SH3 domain-binding Protein SNP70; SIPP1; SNP70; Splicing factor PQBP1 and PP1 interacting; Splicing factor that interacts with PQBP 1 and PP1; Splicing factor that interacts with PQBP-1 and PP1; WBP 11; WBP-11; Wbp11; WBP11_HUMAN; WW domain binding Protein 11; WW domain-binding Protein 11
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Y2W2
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Expression Region
1-641 aa
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AA Sequence
MGRRSTSSTKSGKFMNPTDQARKEARKRELKKNKKQRMMVRAAVLKMKDPKQIIRDMEKLDEMEFNPVQQPQLNEKVLKDKRKKLRETFERILRLYEKENPDIYKELRKLEVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQVVQMYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDVSSTSEDDGYPEDMDQDKHDDSTDDSDTDKSDGESDGDEFVHRDNGERDNNEEKKSGLSVRFADMPGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTALRVRRENKGATAAPQRKSEDDSAVPLAKAAPKSGPSVPVSVQTKDDVYEAFMKEMEGLL
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Molecular Weight
96.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
WBP11, or "WBP11 protein," has garnered significant interest in recent years due to its potential roles in various cellular processes and its involvement in disease mechanisms. This protein is part of the WBP family, which is thought to play crucial roles in cellular signaling and homeostasis. The study of WBP11 is particularly relevant in the context of cancer research, as alterations in its expression and function have been observed in several malignancies. Recent investigations suggest that WBP11 may influence pathways related to cell proliferation, apoptosis, and interactions with other key biomolecules, thereby contributing to tumor progression and metastasis. Furthermore, its potential as a biomarker for specific types of cancer and its role in therapeutic resistance are areas of ongoing research. Understanding the molecular mechanisms underlying WBP11 function could lead to novel therapeutic strategies and improved diagnostic tools, making it an important target for future studies in molecular biology and oncology. By exploring the implications of WBP11 in both normal physiology and disease states, researchers aim to uncover its contributions to cellular dynamics and its promise as a modulator in targeted therapy development.
