Analytical Data
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基因名
ZRF1
- Application
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别名
ZRF1；MPHOSPH11；MPP11；ZRF1；DnaJ homolog subfamily C member 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q99543
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表达区间
2-621aa
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氨基酸序列
LLLPSAADG RGTAITHALT SASTLCQVEP VGRWFEAFVK RRNRNASASF QELEDKKELS EESEDEELQL EEFPMLKTLD PKDWKNQDHY AVLGLGHVRY KATQRQIKAA HKAMVLKHHP DKRKAAGEPI KEGDNDYFTC ITKAYEMLSD PVKRRAFNSV DPTFDNSVPS KSEAKDNFFE VFTPVFERNS RWSNKKNVPK LGDMNSSFED VDIFYSFWYN FDSWREFSYL DEEEKEKAEC RDERRWIEKQ NRATRAQRKK EEMNRIRTLV DNAYSCDPRI KKFKEEEKAK KEAEKKAKAE AKRKEQEAKE KQRQAELEAA RLAKEKEEEE VRQQALLAKK EKDIQKKAIK KERQKLRNSC KTWNHFSDNE AERVKMMEEV EKLCDRLELA SLQCLNETLT SCTKEVGKAA LEKQIEEINE QIRKEKEEAE ARMRQASKNT EKSTGGGGNG SKNWSEDDLQ LLIKAVNLFP AGTNSRWEVI ANYMNIHSSS GVKRTAKDVI GKAKSLQKLD PHQKDDINKK AFDKFKKEHG VVPQADNATP SERFEGPYTD FTPWTTEEQK LLEQALKTYP VNTPERWEKI AEAVPGRTKK DCMKRYKELV EMVKAKKAAQ EQVLNASRAK K
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZRF1 (Zinc Finger RING Finger 1) is a member of the RING finger protein family, known for its roles in various cellular processes, including transcription regulation, DNA repair, and cell cycle progression. Recent studies have highlighted the importance of ZRF1 in the modulation of gene expression and its involvement in critical biological pathways. Researchers have observed that ZRF1 acts as a transcriptional regulator, influencing the expression of genes associated with cell proliferation and differentiation. The protein’s zinc finger motifs are crucial for its DNA-binding capabilities, allowing it to interact with specific genomic regions. Furthermore, ZRF1 has been implicated in oncogenic processes, as altered expression levels have been associated with various cancers. Understanding the molecular mechanisms by which ZRF1 regulates gene expression and its role in tumorigenesis could unveil new therapeutic targets for cancer treatment. The study of ZRF1, particularly through the development and characterization of recombinant ZRF1 proteins, is essential for elucidating its functional dynamics and interactions within the cell. This research not only sheds light on ZRF1's biological significance but also enhances our comprehension of the intricacies of cellular regulation and potential implications in disease. Thus, the investigation into ZRF1 recombinant proteins serves as a vital step towards determining their utility in both basic and applied biomedical research.
