Analytical Data
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Gene name
STX5A
- Application
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Alternative Names
OTTHUMP00000185028; SED5; STX5; STX5_HUMAN; STX5A; Syntaxin 5; Syntaxin 5A; Syntaxin-5; Syntaxin5; Syntaxin5A
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q13190
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Expression Region
1-301 aa
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AA Sequence
MSCRDRTQEFLSACKSLQTRQNGIQTNKPALRAVRQRSEFTLMAKRIGKDLSNTFAKLEKLTILAKRKSLFDDKAVEIEELTYIIKQDINSLNKQIAQLQDFVRAKGSQSGRHLQTHSNTIVVSLQSKLASMSNDFKSVLEVRTENLKQQRSRREQFSRAPVSALPLAPNHLGGGAVVLGAESHASKDVAIDMMDSRTSQQLQLIDEQDSYIQSRADTMQNIESTIVELGSIFQQLAHMVKEQEETIQRIDENVLGAQLDVEAAHSEILKYFQSVTSNRWLMVKIFLILIVFFIIFVVFLA
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Molecular Weight
58.74 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
STX5A, or Syntaxin 5A, is a member of the syntaxin family of proteins, which play crucial roles in intracellular membrane trafficking and fusion processes. Research on STX5A has garnered attention due to its involvement in various cellular functions, including exocytosis, endocytosis, and organelle communication. Emerging studies suggest that dysregulation of STX5A can be linked to several diseases, including neurodegenerative disorders and metabolic syndromes. The protein is believed to interact with other SNARE (Soluble N-ethylmaleimide-sensitive factor Attachment Protein Receptors) proteins, facilitating membrane fusion during vesicle trafficking. As a result, investigating STX5A as a recombinant protein has become essential for understanding its biophysical properties and functional mechanisms in cellular transport pathways. The production of STX5A as a recombinant protein allows for in-depth studies, including crystallization, structural analysis, and functional assays, which can reveal insights into its role in health and disease. Furthermore, understanding the regulatory mechanisms that govern STX5A activity may provide potential therapeutic targets for intervention in pathologies associated with its dysfunction. This research avenue is pivotal for the development of novel strategies aimed at restoring normal cellular processes in diseases where STX5A activity is compromised. Overall, the study of STX5A not only expands our knowledge of membrane biology but also holds promise for identifying new diagnostic and therapeutic avenues in various health conditions.
