Analytical Data
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Gene name
STAU2
- Application
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Alternative Names
39K2; 39K3; DKFZp781K0371; Double stranded RNA binding protein Staufen homolog 2; Double-stranded RNA-binding protein Staufen homolog 2; MGC119606; STAU 2; stau2; STAU2_HUMAN; Staufen (Drosophila; RNA-binding protein) homolog 2; Staufen double-stranded RNA binding protein 2; Staufen homolog 2; Staufen RNA binding protein homolog 2; Staufen; RNA binding protein; homolog 2 (Drosophila)
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NUL3
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Expression Region
1-570 aa
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AA Sequence
MANPKEKTAM CLVNELARFN RVQPQYKLLN ERGPAHSKMF SVQLSLGEQT WESEGSSIKK AQQAVANKAL TESTLPKPVQ KPPKSNVNNN PGSITPTVEL NGLAMKRGEP AIYRPLDPKP FPNYRANYNF RGMYNQRYHC PVPKIFYVQL TVGNNEFFGE GKTRQAARHN AAMKALQALQ NEPIPERSPQ NGESGKDMDD DKDANKSEIS LVFEIALKRN MPVSFEVIKE SGPPHMKSFV TRVSVGEFSA EGEGNSKKLS KKRAATTVLQ ELKKLPPLPV VEKPKLFFKK RPKTIVKAGP EYGQGMNPIS RLAQIQQAKK EKEPDYVLLS ERGMPRRREF VMQVKVGNEV ATGTGPNKKI AKKNAAEAML LQLGYKASTN LQDQLEKTGE NKGWSGPKPG FPEPTNNTPK GILHLSPDVY QEMEASRHKV ISGTTLGYLS PKDMNQPSSS FFSISPTSNS SATIARELLM NGTSSTAEAI GLKGSSPTPP CSPVQPSKQL EYLARIQGFQ AALSALKQFS EQGLDPIDGA MNIEKGSLEK QAKHLREKAD NNQAPPGSIA QDCKKSNSAV
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Molecular Weight
62.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
STAU2, or Staufen double-stranded RNA-binding protein 2, has emerged as a significant player in the field of molecular biology due to its crucial role in RNA metabolism and its involvement in various cellular processes, including mRNA transport, stability, and translation regulation. It acts as a RNA-binding protein that recognizes specific RNA sequences, facilitating the localization of mRNAs within the cell and contributing to the control of gene expression. Research has indicated that STAU2 is involved in important physiological processes such as neuronal development and immune responses, highlighting its potential implications in understanding neurological disorders and diseases associated with immune dysfunction. The recombinant expression of STAU2 protein allows scientists to explore its biophysical properties, functional domains, and interaction with RNA and other cellular factors in more detail. By producing STAU2 as a recombinant protein, researchers can employ various biochemical techniques to study its structure-function relationship and its role in cellular mechanisms. Furthermore, this protein has captivated interest in therapeutic research, as elucidating its mechanism may lead to novel strategies for treating STAU2-related pathologies. The ongoing investigations surrounding the recombinant STAU2 protein not only enhance our understanding of RNA-binding proteins but also add to the broader field of post-transcriptional regulation, making it a critical focus for advancing molecular biology and therapeutic interventions.
