Analytical Data
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Gene name
DMRT2
- Application
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Alternative Names
DMRT2; DMRT2_HUMAN; Doublesex and mab 3 related transcription factor 2; Doublesex- and mab-3-related transcription factor 2; Doublesex-like 2 protein; DSXL 2; DSXL-2; DSXL2; terra like protein
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Y5R5
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Expression Region
1-561aa
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AA Sequence
MADPQAGSAA GDWEIDVESL ELEEDVCGAP RSTPPGPSPP PADGDCEDDE DDDGVDEDAE EEGDGEEAGA SPGMPGQPEQ RGGPQPRPPL APQASPAGTG PRERCTPAGG GAEPRKLSRT PKCARCRNHG VVSCLKGHKR FCRWRDCQCA NCLLVVERQR VMAAQVALRR QQATEDKKGL SGKQNNFERK AVYQRQVRAP SLLAKSILEG YRPIPAETYV GGTFPLPPPV SDRMRKRRAF ADKELENIML EREYKEREML ETSQAAALFL PNRMVPGPDY NSYKSAYSPS PVEPPSKDFC NFLPTCLDLT MQYSGSGNME LISSNVSVAT TYRQYPLSSR FLVWPKCGPI SDTLLYQQCL LNATTSVQAL KPGASWDLKG ARVQDGLSAE QDMMPSKLEG SLVLPHTPEI QTTRSDLQGH QAVPERSAFS PPRRNFSPIV DTDSLAAQGH VLTKISKENT RHPLPLRHNP FHSLFQQTLT DKSGPELKTP FVKEAFEETP KKHRECLVKD NQKYTFTIDR CAKDLFVAKQ VGTKLSVNEP LSFSVESILK RPSSAITRVS Q
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Molecular Weight
61.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DMRT2 (Doublesex and mab-3 related transcription factor 2) is a member of the DMRT (Doublesex and mab-3-related transcription factor) gene family, which plays critical roles in sex determination and differentiation across various species. Research has shown that DMRT2 is involved in the development of the early reproductive system and neural tissues, highlighting its importance in developmental biology. Mutations in DMRT2 are linked to various reproductive disorders, making it a significant target for studying the genetic basis of such conditions. The recombinant protein of DMRT2 is often analyzed to understand its functional properties, binding affinities, and regulatory mechanisms in gene expression. Additionally, studies of DMRT2 recombinant proteins facilitate the exploration of protein interactions, which are essential for elucidating the pathways involved in sexual differentiation and development. By utilizing techniques such as recombinant DNA technology, researchers can produce DMRT2 proteins in vitro, allowing for detailed biochemical assays and structural analyses. This research background emphasizes the protein's significance in both basic and applied biological research, paving the way for potential therapeutic interventions in reproductive health and developmental disorders.
