Analytical Data
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Gene name
DMBX1
- Application
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Alternative Names
DMBX1; MBX; OTX3; PAXBDiencephalon/mesencephalon homeobox protein 1; Orthodenticle homolog 3; Paired-like homeobox protein DMBX1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8NFW5
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Expression Region
1-382aa
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AA Sequence
MQHYGVNGYS LHAMNSLSAM YNLHQQAAQQ AQHAPDYRPS VHALTLAERL AGCTFQDIIL EARYGSQHRK QRRSRTAFTA QQLEALEKTF QKTHYPDVVM RERLAMCTNL PEARVQVWFK NRRAKFRKKQ RSLQKEQLQK QKEAEGSHGE GKAEAPTPDT QLDTEQPPRL PGSDPPAELH LSLSEQSASE SAPEDQPDRE EDPRAGAEDP KAEKSPGADS KGLGCKRGSP KADSPGSLTI TPVAPGGGLL GPSHSYSSSP LSLFRLQEQF RQHMAATNNL VHYSSFEVGG PAPAAAAAAA AVPYLGVNMA PLGSLHCQSY YQSLSAAAAA HQGVWGSPLL PAPPAGLAPA SATLNSKTTS IENLRLRAKQ HAASLGLDTL PN
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Molecular Weight
41.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DMBX1 is a member of the homeobox gene family, known for its critical role in developmental processes, particularly in the formation of the central nervous system and the regulation of various cellular functions. Research has indicated that DMBX1 is essential for the early stages of brain development, influencing neural stem cell differentiation and the establishment of specific neuronal subtypes. Abnormalities in DMBX1 expression have been linked to neurodevelopmental disorders and various malignancies, making it a significant focus of investigation within the fields of developmental biology, neurology, and cancer research. The study of DMBX1 recombinant proteins is particularly valuable as it allows for the elucidation of the gene's functional mechanisms, interactions with other proteins, and its regulatory pathways. By producing and characterizing DMBX1 recombinant proteins, researchers aim to uncover the molecular basis of its actions, providing insights that could lead to potential therapeutic targets for diseases associated with DMBX1 dysregulation. This research not only enhances our understanding of fundamental biological processes but also offers the potential to develop innovative strategies for treating neurodevelopmental and oncological conditions.
