Analytical Data
-
Gene name
DMAP1
- Application
-
Alternative Names
DMAP1; KIAA1425DNA methyltransferase 1-associated protein 1; DNMAP1; DNMT1-associated protein 1
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9NPF5
-
Expression Region
1-467aa
-
AA Sequence
MATGADVRDI LELGGPEGDA ASGTISKKDI INPDKKKSKK SSETLTFKRP EGMHREVYAL LYSDKKDAPP LLPSDTGQGY RTVKAKLGSK KVRPWKWMPF TNPARKDGAM FFHWRRAAEE GKDYPFARFN KTVQVPVYSE QEYQLYLHDD AWTKAETDHL FDLSRRFDLR FVVIHDRYDH QQFKKRSVED LKERYYHICA KLANVRAVPG TDLKIPVFDA GHERRRKEQL ERLYNRTPEQ VAEEEYLLQE LRKIEARKKE REKRSQDLQK LITAADTTAE QRRTERKAPK KKLPQKKEAE KPAVPETAGI KFPDFKSAGV TLRSQRMKLP SSVGQKKIKA LEQMLLELGV ELSPTPTEEL VHMFNELRSD LVLLYELKQA CANCEYELQM LRHRHEALAR AGVLGGPATP ASGPGPASAE PAVTEPGLGP DPKDTIIDVV GAPLTPNSRK RRESASSSSS VKKAKKP
-
Molecular Weight
52.9 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DMAP1 (DNA damage-inducible protein 1) is a protein that has garnered attention in recent years due to its crucial role in various cellular processes, particularly those related to DNA repair and cellular response to stress. Research has shown that DMAP1 is involved in the regulation of gene expression and the maintenance of genome stability, making it a significant player in cancer biology and other diseases linked to genomic instability. Its multifaceted functions include interaction with key proteins involved in transcription and DNA repair pathways, positioning DMAP1 as a potential biomarker for diseases where these processes are disrupted. Furthermore, the study of recombinant DMAP1 protein offers insights into its structure-function relationship, allowing scientists to explore its biochemical properties and interaction dynamics. This research is essential for understanding the molecular mechanisms behind DMAP1's action and its implications in disease pathology, including cancer. By utilizing recombinant technologies, researchers aim to elucidate how DMAP1 can be targeted for therapeutic strategies, potentially leading to novel treatments that leverage its role in maintaining cellular integrity. Overall, the investigation of DMAP1 as a recombinant protein is crucial for advancing our understanding of cellular responses to DNA damage and its broader implications in health and disease.
