Analytical Data
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Gene name
SPATA8
- Application
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Alternative Names
SPATA8; Spermatogenesis-associated protein 8; Spermatogenesis-related protein 8
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6RVD6
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Expression Region
1-105aa
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AA Sequence
MAPAGMSGAQ DNSCLYQEIA PSFQRLPCPR TSSRHFSEAM TCPCGWRPFK GGPGGLKGPV WPAKEENSCS HGRIQRVQRR RVPSASPLIQ KINRRSVLFH PYCWS
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Molecular Weight
11.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SPATA8, or Spermatogenesis Associated 8, is a protein that has garnered increasing attention in the field of cell biology and reproductive medicine due to its critical role in spermatogenesis and potential implications in male fertility. Research indicates that SPATA8 is involved in the regulation of sperm maturation and motility, making it a vital component in the reproductive process. Recent studies have suggested that mutations or dysregulation of SPATA8 may lead to impaired sperm function and contribute to infertility issues. Furthermore, SPATA8 has been linked to various cellular processes, including apoptosis and stress responses, highlighting its significance beyond just reproductive health. The generation of recombinant SPATA8 protein has become a focus of investigation, as it allows for detailed studies of the protein's structure, function, and interactions within cellular pathways. By exploring the dynamics of SPATA8 through recombinant techniques, researchers aim to elucidate its mechanisms of action and potential as a therapeutic target for male infertility. The insights gained from SPATA8 research may also enhance our understanding of related disorders and pave the way for novel strategies in diagnosis and treatment, thus underscoring the importance of this protein in both basic and applied biomedical research.
