Cat: PA2000-7095

Recombinant Human DHRS13 Protein,GST

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Analytical Data

  • 基因名

    DHRS13

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    DHRS13; SDR7C5; UNQ419/PRO853Dehydrogenase/reductase SDR family member 13; EC 1.1.-.-; Short chain dehydrogenase/reductase family 7C member 5

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    GST-tag at N-terminal

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q6UX07

  • 表达区间

    1-327aa

  • 氨基酸序列

    MTALELARRGARVVLACRSQERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGRTREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCRGRLDFKRLDRPVVGWRQELRAYADTKLANVLFARELANQLEATGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASKRLAGLGPGEDAEPDEDPQSEDSEAPSSLSTPHPEEPTVSQPYPSPQSSPDLSKMTHRIQAKVEPEIQLS

  • 分子量

    62.2 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

DHRS13 (Dehydrogenase/Reductase 13) is a member of the short-chain dehydrogenase/reductase (SDR) family, which plays a critical role in various metabolic processes, including steroid metabolism and cellular signaling pathways. The enzyme is characterized by its ability to catalyze the reduction and oxidation of a wide range of substrates, contributing to the regulation of intracellular levels of key metabolites. Recent studies have suggested that DHRS13 may be involved in the metabolites' metabolism and the modulation of oxidative stress, which are vital in various physiological and pathological conditions, including cancer and metabolic disorders. Furthermore, the expression of DHRS13 is regulated by various signaling pathways, highlighting its potential role as an indicator of cellular stress responses. Understanding the structure-function relationships of DHRS13 and its enzymatic activity may provide insights into its biological significance. This has spurred research into elucidating its substrate specificity, reaction mechanisms, and regulatory mechanisms. As DHRS13 emerges as a potential therapeutic target, elucidating its role in human health and disease continues to be a focal point of biochemistry and molecular biology research. Investigating DHRS13’s involvement in metabolic networks could lead to novel strategies for drug development and therapeutic interventions, particularly for diseases characterized by dysregulated metabolic pathways. Thus, understanding the function and regulation of DHRS13 is critical for elucidating its role in metabolism and its potential implications in health and disease management.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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