Cat: PAX2000-11615

Recombinant Human SPATA7 Protein,His

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Analytical Data

  • Gene name

    SPATA7

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    SPATA7; HSD3; Spermatogenesis-associated protein 7; HSD-3.1; Spermatogenesis-associated protein HSD3

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9P0W8

  • Expression Region

    1-599aa

  • AA Sequence

    MDGSRRVRAT SVLPRYGPPC LFKGHLSTKS NAFCTDSSSL RLSTLQLVKN HMAVHYNKIL SAKAAVDCSV PVSVSTSIKY ADQQRREKLK KELAQCEKEF KLTKTAMRAN YKNNSKSLFN TLQKPSGEPQ IEDDMLKEEM NGFSSFARSL VPSSERLHLS LHKSSKVITN GPEKNSSSSP SSVDYAASGP RKLSSGALYG RRPRSTFPNS HRFQLVISKA PSGDLLDKHS ELFSNKQLPF TPRTLKTEAK SFLSQYRYYT PAKRKKDFTD QRIEAETQTE LSFKSELGTA ETKNMTDSEM NIKQASNCVT YDAKEKIAPL PLEGHDSTWD EIKDDALQHS SPRAMCQYSL KPPSTRKIYS DEEELLYLSF IEDVTDEILK LGLFSNRFLE RLFERHIKQN KHLEEEKMRH LLHVLKVDLG CTSEENSVKQ NDVDMLNVFD FEKAGNSEPN ELKNESEVTI QQERQQYQKA LDMLLSAPKD ENEIFPSPTE FFMPIYKSKH SEGVIIQQVN DETNLETSTL DENHPSISDS LTDRETSVNV IEGDSDPEKV EISNGLCGLN TSPSQSVQFS SVKGDNNHDM ELSTLKIMEM SIEDCPLDV

  • Molecular Weight

    67.7 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

SPATA7 (Spermatogenesis Associated 7) is a gene primarily expressed in male germ cells and has been implicated in male fertility and spermatogenesis. Its role in the reproductive system, particularly in the development and function of sperm cells, has garnered significant interest among researchers. Recent studies suggest that SPATA7 may be involved in various cellular processes, including cell signaling, mitochondrial function, and the regulation of gene expression, making it a potential candidate for understanding male infertility issues. Furthermore, the gene has been linked to certain reproductive disorders, suggesting that mutations or dysregulation in SPATA7 could contribute to these conditions. The characterization of SPATA7 recombinant proteins is crucial for in-depth functional studies, as it allows researchers to investigate the protein's structure, interactions, and biological activities in detail. By producing and analyzing SPATA7 recombinant proteins, researchers aim to elucidate its role in germ cell development and to identify potential therapeutic targets for the treatment of male infertility. Additionally, understanding the biochemical properties of SPATA7 could lead to advancements in assisted reproductive technologies. Overall, the study of SPATA7 recombinant proteins is a promising avenue for enhancing our understanding of male reproductive health and addressing related challenges in biomedicine.

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