Cat: PAX2000-11610

Recombinant Human SPATA2 Protein,His

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Analytical Data

  • Gene name

    SPATA2

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    FLJ13167; KIAA0757; PD 1; PD1; PPP1R145; Protein phosphatase 1 regulatory subunit 145; SPAT2_HUMAN; SPATA 2; SPATA2; Spermatogenesis associated 2; Spermatogenesis associated PD1; Spermatogenesis associated protein 2; Spermatogenesis associated protein PD1; Spermatogenesis-associated protein 2; Spermatogenesis-associated protein PD1; Tamo

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9UM82

  • Expression Region

    1-520 aa

  • AA Sequence

    MGKPSSMDTK FKDDLFRKYV QFHESKVDTT TSRQRPGSDE CLRVAASTLL SLHKVDPFYR FRLIQFYEVV ESSLRSLSSS SLRALHGAFS MLETVGINLF LYPWKKEFRS IKTYTGPFVY YVKSTLLEED IRAILSCMGY TPELGTAYKL RELVETLQVK MVSFELFLAK VECEQMLEIH SQVKDKGYSE LDIVSERKSS AEDVRGCSDA LRRRAEGREH LTASMSRVAL QKSASERAAK DYYKPRVTKP SRSVDAYDSY WESRKPPLKA SLSLRKEPVA TDVGDDLKDE IIRPSPSLLT MASSPHGSPD VLPPASPSNG PALLRGTYFS TQDDVDLYTD SEPRATYRRQ DALRPDVWLL RNDAHSLYHK RSPPAKESAL SKCQSCGLSC SSSLCQRCDS LLTCPPASKP SAFPSKASTH DSLAHGASLR EKYPGQTQGL DRLPHLHSKS KPSTTPTSRC GFCNRPGATN TCTQCSKVSC DACLSAYHYD PCYKKSELHK FMPNNQLNYK STQLSHLVYR

  • Molecular Weight

    58.4 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

SPATA2 (Spermatogenesis Associated 2) is a protein believed to play a critical role in male fertility, particularly in sperm development and maturation. Disruptions in SPATA2 expression and function have been linked to various reproductive issues, making it a potential target for understanding infertility mechanisms. Research into SPATA2 has gained traction due to its involvement in spermatogenesis and its interactions with other key proteins in the reproductive system. Studies have shown that SPATA2 is essential for the formation of sperm cells, suggesting that it may be crucial for normal male reproductive function. The exploration of SPATA2 through recombinant protein techniques allows scientists to investigate its structural properties, functional mechanisms, and interactions with other reproductive proteins, thereby advancing our understanding of male fertility. Furthermore, insights gained from SPATA2 research may pave the way for the development of novel therapeutic strategies to address male infertility, highlighting the importance of this protein in reproductive health. As a result, SPATA2 continues to be a significant focus within reproductive biology, with ongoing studies aimed at elucidating its roles and potential clinical applications in fertility treatments.

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