Cat: PAX2000-11608

Recombinant Human SPATA22 Protein,His

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Analytical Data

  • Gene name

    SPATA22

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    SPATA22Spermatogenesis-associated protein 22; Testis development protein NYD-SP20

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8NHS9

  • Expression Region

    1-363 aa

  • AA Sequence

    MKRSLNENSA RSTAGCLPVP LFNQKKRNRQ PLTSNPLKDD SGISTPSDNY DFPPLPTDWA WEAVNPELAP VMKTVDTGQI PHSVSRPLRS QDSVFNSIQS NTGRSQGGWS YRDGNKNTSL KTWNKNDFKP QCKRTNLVAN DGKNSCPVSS GAQQQKQLRI PEPPNLSRNK ETELLRQTHS SKISGCTMRG LDKNSALQTL KPNFQQNQYK KQMLDDIPED NTLKETSLYQ LQFKEKASSL RIISAVIESM KYWREHAQKT VLLFEVLAVL DSAVTPGPYY SKTFLMRDGK NTLPCVFYEI DRELPRLIRG RVHRCVGNYD QKKNIFQCVS VRPASVSEQK TFQAFVKIAD VEMQYYINVM NET

  • Molecular Weight

    41.3 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

SPATA22, or Spermatogenesis Associated 22, is a gene that plays a significant role in spermatogenesis and is primarily expressed in the testes. Research into SPATA22 is driven by its potential implications in male fertility and reproductive health. Studies indicate that mutations or dysregulation of this gene may be linked to various reproductive disorders, including azoospermia and oligozoospermia, which can lead to male infertility. Given the increasing prevalence of infertility globally, understanding the function and mechanism of SPATA22 is critical. Recent investigations have focused on the characterization and functional analysis of SPATA22 recombinant proteins to elucidate their biological roles. These recombinant proteins facilitate the study of SPATA22's interactions with other cellular components and help in identifying pathways involved in sperm development. Additionally, recombinant SPATA22 proteins can serve as valuable tools for the development of diagnostic assays and therapeutic strategies aimed at addressing male infertility. By exploring the structural and functional properties of SPATA22, researchers aim to pave the way for innovative approaches to treat reproductive issues and enhance our understanding of spermatogenesis at the molecular level. Despite the promising findings, more research is necessary to fully decode the intricacies of SPATA22 and its potential as a biomarker for reproductive health.

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