Cat: PAX2000-11607

Recombinant Human SPATA1 Protein,His

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Analytical Data

  • Gene name

    SPATA1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    SPATA1; Spermatogenesis-associated protein 1; Sperm-specific protein SP-2

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q5VX52

  • Expression Region

    1-437 aa

  • AA Sequence

    MSLNPSRPSS SELVELHVFY VPEGSWNYKL NTISTEVVNK FISAGFLRVS PQLTLRALRE RLGEFLGEDA IAEKFLFLKC IGNNLAVVKE KQESELKLKS FAPPYALQPE LYLLPVMDHL GNVYSPSTVI LDERQTNNGV NEADGTIHRP ISVTLFKEEL GRDPSLLENT LKELPNKNQE EAGGKATAEK SQIAKNQIGN SELPGSLEDS NNDCFGTKKS QCLWENEDDT AISRRQDNQT AEKEYITLPD HPSLPCQPVL SSGITDISLL QTEREKIIKQ MKQVKEERRY LERNREELVK TVEKLFEQSK LKRYHAYNGW KKKYLETKKV TASMEEVLTK LREDLELYYK KLLMQLEARE IKMRPKNLAN ITDSKNYLII QITEVQHAID QLKRKLDTDK MKLIVEVKMR KQAVSDLRTL KTELAQKKKI IHLYNLN

  • Molecular Weight

    52.9 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

SPATA1 (Spermatogenesis Associated 1) is a gene that has garnered attention due to its critical role in male fertility and spermatogenesis. Research indicates that SPATA1 is essential for the proper development of sperm, as it is involved in the formation and maturation of germ cells within the testes. Mutations or dysregulation of this gene have been linked to infertility in males, highlighting its importance in reproductive health. The study of SPATA1 recombinant protein has gained momentum as scientists aim to understand its structure and function at a molecular level. Producing SPATA1 as a recombinant protein allows researchers to investigate its interactions with other proteins and cellular pathways, thereby shedding light on the mechanisms underlying spermatogenesis. Furthermore, exploring SPATA1's potential as a biomarker for male fertility can contribute to clinical applications in reproductive medicine. Overall, the research surrounding SPATA1 recombinant protein is pivotal, not only for elucidating the fundamental biological processes of spermatogenesis but also for advancing therapeutic strategies for addressing male infertility.

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