Analytical Data
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Gene name
SPATA19
- Application
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Alternative Names
SPATA19; SPERGEN1; Spermatogenesis-associated protein 19; mitochondrial; Spermatogenic cell-specific gene 1 protein; Spergen-1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q7Z5L4
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Expression Region
25-167 aa
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AA Sequence
SSDIDV VESEAVSVLH HWLKKTEEEA SRGIKEKLSI NHPSQGVREK MSTDSPPTHG QDIHVTRDVV KHHLSKSDLL ANQSQEVLEE RTRIQFIRWS HTRIFQVPSE MTEDIMRDRI EQVRRSISRL TDVSAQDFSM RPSSSDC
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Molecular Weight
19.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SPATA19, or Spermatogenesis Associated 19, is a protein that plays a crucial role in male germ cell development and fertility. Research has shown that SPATA19 is involved in the spermatogenic process, and mutations or dysregulation of this protein may contribute to male infertility. Given the increasing prevalence of infertility issues globally, understanding the molecular mechanisms underlying sperm development is of paramount importance. Studies have indicated that SPATA19 functions in cellular signaling pathways and may interact with several other proteins involved in spermatogenesis. Furthermore, its expression patterns during spermatogenesis suggest a potential role in germ cell maturation. As such, recombinant SPATA19 protein is of significant interest for further investigation, as it could serve as a valuable tool for studying the intricate processes of sperm development and the potential implications of SPATA19 in infertility. Additionally, exploring the biochemical properties and interactions of the recombinant protein could provide insights into its function and the broader spermatogenetic landscape. Overall, SPATA19 research not only enhances our understanding of male reproductive biology but also lays the groundwork for potential therapeutic interventions in treating infertility.
