Analytical Data
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Gene name
SPANXD
- Application
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Alternative Names
Cancer/testis antigen 11.4; Cancer/testis antigen family 11 member 4; CT11.4; dJ171K16.1; Nuclear associated protein SPAN Xd; Nuclear-associated protein SPAN-Xd; SPAN Xd protein; SPANX C; SPANX D; SPANX family member D; SPANX-D; SPANXD; Sperm protein associated with the nucleus on the X chromosome D; Sperm protein associated with the nucleus X chromosome family member D; SPNXD_HUMAN
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BXN6
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Expression Region
1-97 aa
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AA Sequence
MDKQSSAGGV KRSVPCDSNE ANEMMPETSS GYSDPQPAPK KLKTSESSTI LVVRYRRNFK RTSPEELVND HARKNRINPL QMEEEEFMEI MVEIPAK
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Molecular Weight
11.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SPANXD (spermatogenic protein associated with the nuclear envelope during spermatogenesis) is a protein that has garnered attention in reproductive biology, particularly for its role in spermatogenesis and potential implications in male fertility. The research into SPANXD is driven by the need to understand the molecular mechanisms underlying male reproductive health, as infertility affects a significant proportion of couples globally. Studies have suggested that SPANXD is involved in the formation and functionality of sperm cells, and its expression is closely associated with the development of the male germline. Furthermore, alterations in SPANXD expression may correlate with certain infertility conditions, making it a focus of investigation for developing diagnostic and therapeutic strategies. The characterization of SPANXD not only promises insights into normal reproductive processes but also provides a potential biomarker for reproductive disorders. As researchers delve into the protein's structure, function, and regulation, the goal is to illuminate its precise role within the testicular microenvironment, thus enhancing our understanding of male reproductive biology and offering new avenues for infertility treatment.
