Analytical Data
-
Gene name
AGGF1
- Application
-
Alternative Names
AGGF1；GPATC7；GPATCH7；VG5Q；Angiogenic factor with G patch and FHA domains 1
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q8N302
-
Expression Region
2-714aa
-
AA Sequence
ASEAPSPPR SPPPPTSPEP ELAQLRRKVE KLERELRSCK RQVREIEKLL HHTERLYQNA ESNNQELRTQ VEELSKILQR GRNEDNKKSD VEVQTENHAP WSISDYFYQT YYNDVSLPNK VTELSDQQDQ AIETSILNSK DHLQVENDAY PGTDRTENVK YRQVDHFASN SQEPASALAT EDTSLEGSSL AESLRAAAEA AVSQTGFSYD ENTGLYFDHS TGFYYDSENQ LYYDPSTGIY YYCDVESGRY QFHSRVDLQP YPTSSTKQSK DKKLKKKRKD PDSSATNEEK DLNSEDQKAF SVEHTSCNEE ENFANMKKKA KIGIHHKNSP PKVTVPTSGN TIESPLHENI SNSTSFKDEK IMETDSEPEE GEITDSQTED SYDEAITSEG NVTAEDSEDE DEDKIWPPCI RVIVIRSPVL QIGSLFIITA VNPATIGREK DMEHTLRIPE VGVSKFHAEI YFDHDLQSYV LVDQGSQNGT IVNGKQILQP KTKCDPYVLE HGDEVKIGET VLSFHIHPGS DTCDGCEPGQ VRAHLRLDKK DESFVGPTLS KEEKELERRK ELKKIRVKYG LQNTEYEDEK TLKNPKYKDR AGKRREQVGS EGTFQRDDAP ASVHSEITDS NKGRKMLEKM GWKKGEGLGK DGGGMKTPIQ LQLRRTHAGL GTGKPSSFED VHLLQNKNKK NWDKARERFT ENFPETKPQK DDPGTMPWVK GTLE
-
Molecular Weight
12 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
AGGF1 (angiogenic factor with GPatch and FHA domains 1) is a protein that has garnered attention in recent years due to its role in promoting angiogenesis, the formation of new blood vessels from pre-existing ones, which is a critical process in both normal physiological functions and pathological conditions such as cancer and ischemia. Initially identified as a putative oncogene, AGGF1 is involved in various cellular processes, including vascular endothelial cell proliferation and migration, thus playing a significant part in the regulation of blood vessel formation. Studies suggest that AGGF1 can modulate the signaling pathways associated with vascular growth factors, such as VEGF (vascular endothelial growth factor). Furthermore, AGGF1 has been implicated in several diseases where abnormal angiogenesis occurs, making it a potential target for therapeutic interventions. Investigations into the structure and function of AGGF1 have highlighted its unique domains, which may be crucial for its interaction with other proteins and regulatory mechanisms in angiogenesis. The development of AGGF1 recombinant protein for research purposes allows a deeper understanding of its biological functions and potential roles in disease processes. By exploring AGGF1's mechanisms, researchers aim to discover new approaches for treating conditions associated with aberrant blood vessel growth, thereby contributing to the advancement of targeted therapies in oncology and regenerative medicine.
