Cat: PA2000-3410

Recombinant Human GDAP2 Protein,His

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Analytical Data

  • Gene name

    GDAP2

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    GDAP2;Ganglioside-induced differentiation-associated Protein 2

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9NXN4

  • Expression Region

    1-496aa

  • AA Sequence

    MDPLGAPSQFVDVDTLPSWGDSCQDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGETIEKVVFAVSDLEEGTYQKLLPLYFPRSLKEENRSLPYLPADIGNAEGEPVVPERQIRISEKPGAPEDNQEEEDEGLGVDLSFIGSHAFARMEGDIDKQRKLILQGQLSEAALQKQHQRNYNRWLCQARSEDLSDIASLKALYQTGVDNCGRTVMVVVGRNIPVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYDARVRSTRSSPSPGMVY

  • Molecular Weight

    72.0 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

GDAP2 (Ganglioside-Induced Differentiation-Associated Protein 2) is a member of the GDAP family, which has been implicated in neuronal differentiation and development. Its role in various neurological conditions has garnered significant attention, particularly in the context of peripheral neuropathies and neurodegenerative diseases. The research into GDAP2 recombinant proteins aims to elucidate the underlying mechanisms of its function and its interaction with other cellular pathways. By generating recombinant GDAP2 proteins, scientists can investigate their biochemical properties, expression patterns, and functional roles in cellular models. Studies have shown that alterations in GDAP2 expression levels can influence neuronal cell survival and apoptosis, making it a potential therapeutic target for conditions linked to neuronal degeneration. Understanding the structure and function of GDAP2 can also contribute to the development of diagnostic markers for related diseases. Overall, the exploration of GDAP2 recombinant proteins is crucial for uncovering the complexities of neuronal biology and advancing therapeutic strategies for neurodegenerative disorders.

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