Analytical Data
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Gene name
LIMS1
- Application
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Alternative Names
LIMS1；PINCH；PINCH1；LIM and senescent cell antigen-like-containing domain Protein 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P48059
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Expression Region
1-325aa
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AA Sequence
MANALASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLF YEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLC QEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIFK NDPYHPDHFNCANCGKELTADARELKGELYCLPCHDKMGVPICGACRRPI EGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGD VCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVC KKCYEKFPLELKKRLKKLAETLGRK
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Molecular Weight
62 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
LIMS1 (LIM domain-containing scaffolding protein 1) is a crucial element in cellular signaling and organization, notably associated with various cellular functions including cytoskeletal dynamics, cell adhesion, and signal transduction. Its role in modulating the behavior of different cell types has garnered attention in the field of molecular biology and biochemistry. The study of recombinant LIMS1 protein has emerged due to its potential implications in understanding cell development and differentiation processes as well as its involvement in various diseases, including cardiovascular and neurological disorders. The recombinant expression of LIMS1 allows for detailed biophysical and biochemical characterization, enabling researchers to dissect its functional properties and interactions with other cellular proteins. Furthermore, the elucidation of its structure-function relationship aids in deciphering the molecular mechanisms underlying its role in cellular pathways. Research into LIMS1 also holds promise for the development of novel therapeutic strategies, as targeting its interactions could provide new avenues for treating conditions associated with dysregulated signaling pathways. Overall, the exploration of LIMS1 recombinant protein unveils critical insights into its biological significance and therapeutic potential.
